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1.1.3.21: glycerol-3-phosphate oxidase

This is an abbreviated version!
For detailed information about glycerol-3-phosphate oxidase, go to the full flat file.

Word Map on EC 1.1.3.21

Reaction

sn-glycerol 3-phosphate
+
O2
=
glycerone phosphate
+
H2O2

Synonyms

alpha-glycerol-3-phosphate oxidase, alpha-glycerophosphate oxidase, G2POx, GLPD, GlpO, GlpO protein, glycerol phosphate oxidase, glycerol-1-phosphate oxidase, glycerol-3-P oxidase, Glycerol-3-phosphate oxidase, GP oxidase, GPO, IhgO, L-alpha-glycerol-3-phosphate oxidase, L-alpha-glycerophosphate oxidase, oxidase, glycerol phosphate

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.21 glycerol-3-phosphate oxidase

Engineering

Engineering on EC 1.1.3.21 - glycerol-3-phosphate oxidase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D55H
mutant isolated from children and teens with bronchitis and pneumonia diagnoses, mutant displays 250% increase in H2O2 production. Mutant shows increased cytotoxicity to respiratory epithelium cells
H51L
mutant isolated from children and teens with bronchitis and pneumonia diagnoses, mutant displays 50% reduction in H2O2 production. Mutant shows decreased cytotoxicity to respiratory epithelium cells
L61V
mutant isolated from children and teens with bronchitis and pneumonia diagnoses, mutant displays no change in H2O2 production
additional information