Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2,6-dichlorophenolindophenol
-
inhibition by excess substrate
2-hydroxybutynoate
-
inhibition of transhydrogenation reaction
2-oxobutyrate
-
non-competitive inhibition at 5 mM
2-oxoisocaproate
-
non-competitive inhibition at 5 mM, most active inhibitor of 2-keto acids, oxidation of 2-hydroxybutyrate most sensitive
2-oxoisovalerate
-
non-competitive inhibition at 5 mM
2-oxovalerate
-
non-competitive inhibition at 5 mM
2-pyridylhydroxymethanesulfonate
-
strong inhibition between 0.1-1 mM
3-benzyl-4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-1H-pyrazole-5-carboxylic acid
3-decyl-2,5-dioxo-4-hydroxy-3-pyrroline
-
bound to the active site in the three-dimensional structure
3-ethoxy-4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-1H-pyrazole-5-carboxylic acid
3-ethyl-4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-(2-phenoxybenzyl)-1H-pyrazole-5-carboxylic acid
3-methyl-4-(2-phenylethyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(3-phenoxybenzyl)-1H-pyrazole-5-carboxylic acid
3-methyl-4-(4-phenoxybenzyl)-1H-pyrazole-5-carboxylic acid
3-methyl-4-(naphthalen-1-ylmethyl)-1H-pyrazole-5-carboxylic acid
3-methyl-4-(naphthalen-2-ylmethyl)-1H-pyrazole-5-carboxylic acid
3-methyl-4-(quinolin-2-ylmethyl)-1H-pyrazole-5-carboxylic acid
3-methyl-4-[2-(trifluoromethoxy)benzyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-[2-(trifluoromethyl)benzyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-[3-(pyridin-3-yl)benzyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-[3-(pyridin-4-yl)benzyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-[3-(trifluoromethyl)benzyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-[4-(trifluoromethoxy)benzyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-[4-(trifluoromethyl)benzyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-[[4'-(trifluoromethoxy)biphenyl-3-yl]methyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-[[4'-(trifluoromethoxy)biphenyl-4-yl]methyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-[[4'-(trifluoromethyl)biphenyl-3-yl]methyl]-1H-pyrazole-5-carboxylic acid
3-methyl-4-[[4'-(trifluoromethyl)biphenyl-4-yl]methyl]-1H-pyrazole-5-carboxylic acid
4-(1-benzofuran-2-ylmethyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(1-benzothiophen-2-ylmethyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(3-carbamoylbenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(3-carboxybenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(3-cyanobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(3-fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(4'-fluorobiphenyl-3-yl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(4'-fluorobiphenyl-4-yl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(4-carbamoylbenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(4-carboxybenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(4-cyanobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(4-fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(4-fluorophenyl)-3-methyl-1H-pyrazole-5-carboxylic acid
4-(biphenyl-3-ylmethyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-carboxy-5-(1-pentyl)hexylsulfanyl-1,2,3-triazole
-
bound to the active site in the three-dimensional structure
4-carboxy-5-dodecylsulfanyl-1,2,3-triazole
-
4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole
CCPST
4-[(2'-fluorobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[(3'-fluorobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[(4'-carbamoylbiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[(4'-carboxybiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[(4'-cyanobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[(4'-fluorobiphenyl-2-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[(4'-fluorobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[(4'-fluorobiphenyl-4-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[2-(4'-fluorobiphenyl-3-yl)ethyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[2-(4'-fluorobiphenyl-4-yl)ethyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[2-(4-fluorophenyl)ethyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[2-(biphenyl-4-yl)ethyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[[4'-(2-amino-2-oxoethyl)biphenyl-3-yl]methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-3-(2-phenylethyl)-1H-pyrazole-5-carboxylic acid
4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-3-(propan-2-yl)-1H-pyrazole-5-carboxylic acid
4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-3-phenyl-1H-pyrazole-5-carboxylic acid
arsenate
-
inhibition of glycolate-ferricyanide or glyoxylate-ferricyanide assay above 0.1 M
Atebrin
-
long chain oxidase, 72-76% inhibition at 1 mM, short chain oxidase: 68-76% inhibition at 1 mM
benzaldehyde
-
50% inhibition at 2 mM
bipyridine
-
strong inhibition
caproate
-
mixed-type non-competitive inhibition
chloride
inhibits the enzyme at high concentrations
Cibacron blue 3GA
-
at a concentration higher than 0.001 mM is a normal competitive inhibitor, at concentrations below 0.001 mM the inhibition is time-, dye- and pH-dependent
cysteine
-
28-38% inhibition of glycolate oxidation at 1 mM
dihydrolipoate
-
competitive inhibition of 2-hydroxybutyrate oxidation
Dithionite
-
reduction of FMN
DL-2-hydroxy-3-butynoate
-
irreversible inactivation after 25 turnovers, covalent addition to the coenzyme
DL-2-hydroxy-3-heptynoate
-
inactivation after18000 turnovers
DL-2-hydroxy-3-hexynoate
-
inactivation after 8500 turnovers
DL-2-hydroxy-3-octynoate
-
inactivation after 15000 turnovers
DL-2-hydroxy-3-pentynoate
-
inactivation after 4800 turnovers
DL-2-hydroxyisocaproate
-
marked inhibition above 50 mM
DL-2-hydroxyvalerate
-
marked inhibition above 50 mM
DL-beta-Phenyllactate
-
short chain oxidase: 10% inhibition of glycolate oxidation, 81% inhibition of L-2-hydroxisocaproate oxidation at 10 mM
DL-Lipoate
-
long chain oxidase, 35% inhibition at 0.24 mM, short chain oxidase: 46-52% inhibition at 0.01 mM
DL-vinylglycolate
-
slight inactivation after 10000 turnovers
hydoxylamine
-
66-67% inhibition at 5 mM
hydroxylamine
-
50% inhibition at 5 mM, competitive
iodoacetamide
-
inhibition at 50 mM
L-phenylalanine
-
long chain oxidase, 43% inhibition at 33 mM
oxamate
-
mixed-type non-competitive inhibition
Quinacrine
-
6% inhibition at 1 mM
rotenone
-
50% inhibition at 0.1 mM
sodium sulfite
-
reduces FMN
trans-cinnamate
-
competitive inhibition
2-Hydroxybutyrate
-
at pH 7.0
2-Hydroxybutyrate
-
long chain oxidase, 13-17% inhibition at 17 mM
3-benzyl-4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-benzyl-4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-ethoxy-4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-ethoxy-4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-ethyl-4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-ethyl-4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(2-phenoxybenzyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(2-phenoxybenzyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(3-phenoxybenzyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(3-phenoxybenzyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(4-phenoxybenzyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(4-phenoxybenzyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(naphthalen-1-ylmethyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(naphthalen-1-ylmethyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(naphthalen-2-ylmethyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(naphthalen-2-ylmethyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(quinolin-2-ylmethyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-(quinolin-2-ylmethyl)-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[2-(trifluoromethoxy)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[2-(trifluoromethoxy)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[2-(trifluoromethyl)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[2-(trifluoromethyl)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[3-(pyridin-3-yl)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[3-(pyridin-3-yl)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[3-(pyridin-4-yl)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[3-(pyridin-4-yl)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[3-(trifluoromethyl)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[3-(trifluoromethyl)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[4-(trifluoromethoxy)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[4-(trifluoromethoxy)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[4-(trifluoromethyl)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[4-(trifluoromethyl)benzyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[[4'-(trifluoromethoxy)biphenyl-3-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[[4'-(trifluoromethoxy)biphenyl-3-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[[4'-(trifluoromethoxy)biphenyl-4-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[[4'-(trifluoromethoxy)biphenyl-4-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[[4'-(trifluoromethyl)biphenyl-3-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[[4'-(trifluoromethyl)biphenyl-3-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[[4'-(trifluoromethyl)biphenyl-4-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
3-methyl-4-[[4'-(trifluoromethyl)biphenyl-4-yl]methyl]-1H-pyrazole-5-carboxylic acid
-
-
4-(1-benzofuran-2-ylmethyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(1-benzofuran-2-ylmethyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(1-benzothiophen-2-ylmethyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(1-benzothiophen-2-ylmethyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(3-carbamoylbenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(3-carbamoylbenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(3-carboxybenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(3-carboxybenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(3-cyanobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(3-cyanobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(3-fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(3-fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4'-fluorobiphenyl-3-yl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4'-fluorobiphenyl-3-yl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4'-fluorobiphenyl-4-yl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4'-fluorobiphenyl-4-yl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4-carbamoylbenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4-carbamoylbenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4-carboxybenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4-carboxybenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4-cyanobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4-cyanobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4-fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4-fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4-fluorophenyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-(4-fluorophenyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
35% inhibition at 0.010 mM
4-(4-fluorophenyl)-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-chloromercuribenzoate
-
strong inhibition at 0.01 mM
4-chloromercuribenzoate
-
inhibition at 50 mM
4-chloromercuribenzoate
-
long chain oxidase, 29-42% inhibition at 0.001 mM, short chain oxidase: 70-75% inhibition at 0.001 mM
4-[(2'-fluorobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(2'-fluorobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(3'-fluorobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(3'-fluorobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-carbamoylbiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-carbamoylbiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-carboxybiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-carboxybiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-cyanobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-cyanobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-fluorobiphenyl-2-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-fluorobiphenyl-2-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-fluorobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-fluorobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-fluorobiphenyl-4-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[(4'-fluorobiphenyl-4-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[2-(4'-fluorobiphenyl-3-yl)ethyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[2-(4'-fluorobiphenyl-3-yl)ethyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[2-(4'-fluorobiphenyl-4-yl)ethyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[2-(4'-fluorobiphenyl-4-yl)ethyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[2-(4-fluorophenyl)ethyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[2-(4-fluorophenyl)ethyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[[4'-(2-amino-2-oxoethyl)biphenyl-3-yl]methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[[4'-(2-amino-2-oxoethyl)biphenyl-3-yl]methyl]-3-methyl-1H-pyrazole-5-carboxylic acid
-
-
4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-3-(2-phenylethyl)-1H-pyrazole-5-carboxylic acid
-
-
4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-3-(2-phenylethyl)-1H-pyrazole-5-carboxylic acid
-
-
4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-3-(propan-2-yl)-1H-pyrazole-5-carboxylic acid
-
-
4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-3-(propan-2-yl)-1H-pyrazole-5-carboxylic acid
-
-
4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-3-phenyl-1H-pyrazole-5-carboxylic acid
-
-
4-[[4-(4-fluorophenyl)pyridin-2-yl]methyl]-3-phenyl-1H-pyrazole-5-carboxylic acid
-
-
8-hydroxyquinoline
-
50% inhibition at 0.05 mM
8-hydroxyquinoline
-
5-17% inhibition at 1 mM
8-hydroxyquinoline
-
8-17% inhibition at 1 mM
acetate
-
mixed-type non-competitive inhibition
Cu2+
-
nearly complete inhibition at 0.025 mM
Cu2+
-
complete inhibition at 0.025 mM
Cu2+
-
50% inhibition at 0.2 mM
Cu2+
-
short chain oxidase: 86% inhibition at 0.1 mM
diethyldithiocarbamate
-
competitive inhibition
diethyldithiocarbamate
-
51-55% inhibition at 1 mM
diphenylglycolic acid
-
11-17% inhibition at 52 mM
diphenylglycolic acid
-
50% inhibition at 52 mM, competitive
glycolate
-
-
glycolate
-
inhibition by excess substrate
glycolate
-
inhibition above 1.7 mM
glyoxylate
-
inhibition by excess substrate
glyoxylate
substrate inhibition at concentrations above 4 mM
iodoacetate
-
inhibition at 50 mM
iodoacetate
-
long chain oxidase, 31-36% inhibition at 0.1 mM, short chain oxidase: no inhibition
KCN
-
mixed-type inhibitor
KCN
-
30% inhibition of L-2-hydroxyisocaproate oxidation at 1 mM, 91% inhibition of glycolate oxidation at 1 mM
L-leucine
-
competitive inhibition
L-leucine
-
9-12% inhibition at 33 mM
L-Mandelate
-
at pH 7.0
L-Mandelate
-
inhibition by excess substrate
o-Iodosobenzoate
-
46-62% inhibition at 0.1 mM
o-Iodosobenzoate
-
46% inhibition at 0.1 mM
o-Iodosobenzoate
-
long chain oxidase, 95-100% inhibition at 0.1 mM, short chain oxidase: no inhibition
o-phenanthroline
-
strong inhibition between 0.1-1.0 mM
o-phenanthroline
-
5-23% inhibition at 1 mM
o-phenanthroline
-
5-14% inhibition at 1 mM
oxalate
-
at pH 7.0
oxalate
-
mixed-type non-competitive inhibition, increasing inhibitory effects as the number of carbons in aliphatic chains decreases
oxalate
-
competitive inhibition
oxalate
-
18% inhibition of glycolate oxidation, 71% inhibition of glyoxylate oxidation at 0.03 mM
oxalate
-
34% inhibition at 5 mM, competitive
phosphate
-
competitive
phosphate
-
50% inhibition at 0.1 M
phosphate
-
inhibition of glycolate-ferricyanide or glyoxylate-ferricyanide assay above 0.1 M
propionate
-
mixed-type non-competitive inhibition
pyruvate
-
competitive inhibition
pyruvate
-
26% inhibition at 5 mM
succinate
-
-
succinate
-
mesophyll isoform
additional information
-
development of selective inhibitors of Hao2 from screening of a compound library, overview
-
additional information
-
treatment with 4-[(4'-fluorobiphenyl-3-yl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid or 4-(1-benzothiophen-2-ylmethyl)-3-methyl-1H-pyrazole-5-carboxylic acid results in a significant reduction or attenuation of blood pressure in an established or developing model of hypertension, deoxycorticosterone acetate-treated rats
-
additional information
-
development of selective inhibitors of Hao2 from screening of a compound library, overview
-