1.1.1.B51: 3-quinuclidinone reductase (NADPH)

This is an abbreviated version, for detailed information about 3-quinuclidinone reductase (NADPH), go to the full flat file.

Reaction

(R)-3-quinuclidinol
+
NADP+
=
3-quinuclidinone
+
NADPH
+
H+

Synonyms

RrQR

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B51 3-quinuclidinone reductase (NADPH)

Crystallization

Crystallization on EC 1.1.1.B51 - 3-quinuclidinone reductase (NADPH)

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Crystallization/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
sitting-drop vapor-diffusion method with a reservoir solution containing 100 mM CHES (pH 10.0), 30% PEG8000, and 3% sucrose, at 5°C
-
sitting-drop vapour-diffusion method using PEG 8000 as the precipitant. The crystals belonged to space group P4(1)2(1)2, with unit-cell parameters a = b = 91.3, c = 265.4 A, and diffracted X-rays to 2.2 A resolution.The asymmetric unit contained four molecules of the protein and the solvent content was 48.4%
-