1.1.1.B47: succinate semialdehyde reductase (NADPH)

This is an abbreviated version, for detailed information about succinate semialdehyde reductase (NADPH), go to the full flat file.

Reaction

4-hydroxybutanoate
+
NADP+
=
succinate semialdehyde
+
NADPH
+
H+

Synonyms

At3g25530, AtGLYR1, Msed_1424, SSA, succinate semialdehyde reductase, succinic semialdehyde reductase, succinic semialdehyde reductase (NADPH)

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B47 succinate semialdehyde reductase (NADPH)

KM Value

KM Value on EC 1.1.1.B47 - succinate semialdehyde reductase (NADPH)

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.18
NADH
65°C, pH 7.9
0.0022 - 0.006
NADPH
0.052
succinate semialdehyde
65°C, pH 7.9, cosubstrate: NADPH
0.87
Succinic semialdehyde
pH 7.8, temperature not specified in the publication, recombinant wild-type enzyme, value determined with the use of a double beam spectrophotometer
additional information
additional information
Michaelis-Menten kinetics, the activities of the mutant enzymes with succinic semialdehyde are generally too low for kinetic studies
-