1.1.1.B3: (S)-specific secondary alcohol dehydrogenase

This is an abbreviated version, for detailed information about (S)-specific secondary alcohol dehydrogenase, go to the full flat file.

Reaction

(S)-R-CHOH-R'
+
NAD+
=
R-CO-R'
+
NADH
+
H+

Synonyms

(S)-1-phenylethanol dehydrogenase, ADH, ADH1, ADH2, ADHTt, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CRII, More, NAD+-dependent (S)-stereospecific alcohol dehydrogenase, PED, SADH, short-chain NAD(H)-dependent alcohol dehydrogenase, TtADH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B3 (S)-specific secondary alcohol dehydrogenase

Temperature Stability

Temperature Stability on EC 1.1.1.B3 - (S)-specific secondary alcohol dehydrogenase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
25
-
phosphate buffer, pH 7.0, 7 h, 80% residual activity
40
Nocardia fusca AKU 2123
-
30 min, pH 7.0, 85% residual activity
60
-
24 h, purified recombinant enzyme, 134% inactivation
additional information
-
the thermal stability of the enzyme adsorbed by ionic exchange is very similar to the stability of the covalently immobilized enzymes in the pH range 5-9, thermal inactivation kinetics, overview