1.1.1.B3: (S)-specific secondary alcohol dehydrogenase

This is an abbreviated version, for detailed information about (S)-specific secondary alcohol dehydrogenase, go to the full flat file.

Reaction

(S)-R-CHOH-R'
+
NAD+
=
R-CO-R'
+
NADH
+
H+

Synonyms

(S)-1-phenylethanol dehydrogenase, ADH, ADH1, ADH2, ADHTt, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CRII, More, NAD+-dependent (S)-stereospecific alcohol dehydrogenase, PED, SADH, short-chain NAD(H)-dependent alcohol dehydrogenase, TtADH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B3 (S)-specific secondary alcohol dehydrogenase

KM Value

KM Value on EC 1.1.1.B3 - (S)-specific secondary alcohol dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4.2
(S)-1-indanol
-
pH 6.0, 65C, recombinant enzyme, reduction reaction
0.0055
(S)-1-phenylethanol
-
pH 7.8, 25C
0.012 - 29.8
(S)-2-butanol
0.33
(S)-2-hexanol
Nocardia fusca AKU 2123
-
30C, pH 7.5
0.07 - 8.8
(S)-2-pentanol
1.6
(S)-3-pentyn-2-ol
Nocardia fusca AKU 2123
-
30C, pH 7.5
27.6
1-Indanone
-
pH 6.0, 65C, recombinant enzyme, reduction reaction
2.5
2-Hexanone
Nocardia fusca AKU 2123
-
30C, pH 7.5
0.0113 - 0.153
acetophenone
5.8
alpha-tetralone
-
pH 6.0, 65C, recombinant enzyme, reduction reaction
3.3
ethyl 4-chloro-3-oxobutanoate
pH 6.0, 30C
0.157
NADH
-
pH 7.0, 25C
5.1
rac-1-indanol
-
pH 6.0, 65C, recombinant enzyme, reduction reaction
5.3
rac-alpha-tetralol
-
pH 6.0, 65C, recombinant enzyme, reduction reaction
additional information
additional information
-