1.1.1.B3: (S)-specific secondary alcohol dehydrogenase

This is an abbreviated version, for detailed information about (S)-specific secondary alcohol dehydrogenase, go to the full flat file.

Reaction

(S)-R-CHOH-R'
+
NAD+
=
R-CO-R'
+
NADH
+
H+

Synonyms

(S)-1-phenylethanol dehydrogenase, ADH, ADH1, ADH2, ADHTt, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CRII, More, NAD+-dependent (S)-stereospecific alcohol dehydrogenase, PED, SADH, Scr2, short-chain NAD(H)-dependent alcohol dehydrogenase, SOU1, TtADH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B3 (S)-specific secondary alcohol dehydrogenase

Activating Compound

Activating Compound on EC 1.1.1.B3 - (S)-specific secondary alcohol dehydrogenase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
2 mM, 115% of initial activity
o-phenanthroline
-
activates to 108% activity compared to the control activity at 0.1 mM and to 109% at 1 mM
Triton X-100
1%, 112% of initial activity
Tween-20
1%, 111% of initial activity
Tween-80
1%, 115% of initial activity
additional information
not inhibitory or activating: EDTA, dithiothreitol
-