1.1.1.B20: meso-2,3-butandiol dehydrogenase

This is an abbreviated version, for detailed information about meso-2,3-butandiol dehydrogenase, go to the full flat file.

Reaction

(2R,3S)-butane-2,3-diol
+
NAD+
=
acetoin
+
NADH
+
H+

Synonyms

2,3-BD dehydrogenase, ARA1, BDH, meso-2,3-BDH, meso-2,3-butanediol dehydrogenase, meso-BD, NAD(H)-dependent meso-2,3-BDH, NAD(H)-dependent meso-2,3-butanediol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B20 meso-2,3-butandiol dehydrogenase

Reference

Reference on EC 1.1.1.B20 - meso-2,3-butandiol dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Otagiri, M.; Kurisu, G.; Ui, S.; Takusagawa, Y.; Ohkuma, M.; Kudo, T.; Kusunoki, M.
Crystal structure of meso-2,3-butanediol dehydrogenase in a complex with NAD+ and inhibitor mercaptoethanol at 1.7 A resolution for understanding of chiral substrate recognition mechanisms
J. Biochem.
129
205-208
2001
Klebsiella pneumoniae
Manually annotated by BRENDA team
Ui, S.; Mimura, A.; Ohkuma, M.; Kudo, T.
Formation of a chiral acetoinic compound from diacetyl by Escherichia coli expressing meso-2,3-butanediol dehydrogenase
Lett. Appl. Microbiol.
28
457-460
1999
Klebsiella pneumoniae
Manually annotated by BRENDA team
Nielsen, D.R.; Yoon, S.H.; Yuan, C.J.; Prather, K.L.
Metabolic engineering of acetoin and meso-2, 3-butanediol biosynthesis in E. coli
Biotechnol. J.
5
274-284
2010
Escherichia coli, Saccharomyces cerevisiae
Manually annotated by BRENDA team
Gonzalez, E.; Fernandez, M.R.; Marco, D.; Calam, E.; Sumoy, L.; Pares, X.; Dequin, S.; Biosca, J.A.
Role of Saccharomyces cerevisiae oxidoreductases Bdh1p and Ara1p in the metabolism of acetoin and 2,3-butanediol
Appl. Environ. Microbiol.
76
670-679
2010
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Otagiri, M.; Ui, S.; Takusagawa, Y.; Ohtsuki, T.; Kurisu, G.; Kusunoki, M.
Structural basis for chiral substrate recognition by two 2,3-butanediol dehydrogenases
FEBS Lett.
584
219-223
2010
Corynebacterium glutamicum
Manually annotated by BRENDA team
Zhang, L.; Xu, Q.; Zhan, S.; Li, Y.; Lin, H.; Sun, S.; Sha, L.; Hu, K.; Guan, X.; Shen, Y.
A new NAD(H)-dependent meso-2,3-butanediol dehydrogenase from an industrially potential strain Serratia marcescens H30
Appl. Microbiol. Biotechnol.
98
1175-1184
2014
Serratia marcescens (H9XP47), Serratia marcescens, Serratia marcescens H30 (H9XP47), Serratia marcescens H30
Manually annotated by BRENDA team
Zhang, G.L.; Wang, C.W.; Li, C.
Cloning, expression and characterization of meso-2,3-butanediol dehydrogenase from Klebsiella pneumoniae
Biotechnol. Lett.
34
1519-1523
2012
Klebsiella pneumoniae, Klebsiella pneumoniae XJ-Li
Manually annotated by BRENDA team