1.1.1.B20: meso-2,3-butandiol dehydrogenase

This is an abbreviated version, for detailed information about meso-2,3-butandiol dehydrogenase, go to the full flat file.

Reaction

(2R,3S)-butane-2,3-diol
+
NAD+
=
acetoin
+
NADH
+
H+

Synonyms

2,3-BD dehydrogenase, 2,3-butanediol dehydrogenae, ADH-9, ARA1, BDH, budC, butACg, mbdh, meso-2,3-BD dehydrogenase, meso-2,3-BDH, meso-2,3-butanediol dehydrogenase, meso-acetoin reductase, meso-BD, meso-BDH, NAD(H)-dependent meso-2,3-BDH, NAD(H)-dependent meso-2,3-butanediol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B20 meso-2,3-butandiol dehydrogenase

Reference

Reference on EC 1.1.1.B20 - meso-2,3-butandiol dehydrogenase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Otagiri, M.; Kurisu, G.; Ui, S.; Takusagawa, Y.; Ohkuma, M.; Kudo, T.; Kusunoki, M.
Crystal structure of meso-2,3-butanediol dehydrogenase in a complex with NAD+ and inhibitor mercaptoethanol at 1.7 A resolution for understanding of chiral substrate recognition mechanisms
J. Biochem.
129
205-208
2001
Klebsiella pneumoniae
Manually annotated by BRENDA team
Ui, S.; Mimura, A.; Ohkuma, M.; Kudo, T.
Formation of a chiral acetoinic compound from diacetyl by Escherichia coli expressing meso-2,3-butanediol dehydrogenase
Lett. Appl. Microbiol.
28
457-460
1999
Klebsiella pneumoniae
Manually annotated by BRENDA team
Nielsen, D.R.; Yoon, S.H.; Yuan, C.J.; Prather, K.L.
Metabolic engineering of acetoin and meso-2, 3-butanediol biosynthesis in E. coli
Biotechnol. J.
5
274-284
2010
Escherichia coli, Saccharomyces cerevisiae
Manually annotated by BRENDA team
Gonzalez, E.; Fernandez, M.R.; Marco, D.; Calam, E.; Sumoy, L.; Pares, X.; Dequin, S.; Biosca, J.A.
Role of Saccharomyces cerevisiae oxidoreductases Bdh1p and Ara1p in the metabolism of acetoin and 2,3-butanediol
Appl. Environ. Microbiol.
76
670-679
2010
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Otagiri, M.; Ui, S.; Takusagawa, Y.; Ohtsuki, T.; Kurisu, G.; Kusunoki, M.
Structural basis for chiral substrate recognition by two 2,3-butanediol dehydrogenases
FEBS Lett.
584
219-223
2010
Corynebacterium glutamicum
Manually annotated by BRENDA team
Zhang, L.; Xu, Q.; Zhan, S.; Li, Y.; Lin, H.; Sun, S.; Sha, L.; Hu, K.; Guan, X.; Shen, Y.
A new NAD(H)-dependent meso-2,3-butanediol dehydrogenase from an industrially potential strain Serratia marcescens H30
Appl. Microbiol. Biotechnol.
98
1175-1184
2014
Serratia marcescens (H9XP47), Serratia marcescens, Serratia marcescens H30 (H9XP47)
Manually annotated by BRENDA team
Zhang, G.L.; Wang, C.W.; Li, C.
Cloning, expression and characterization of meso-2,3-butanediol dehydrogenase from Klebsiella pneumoniae
Biotechnol. Lett.
34
1519-1523
2012
Klebsiella pneumoniae, Klebsiella pneumoniae XJ-Li
Manually annotated by BRENDA team
Rados, D.; Turner, D.L.; Catarino, T.; Hoffart, E.; Neves, A.R.; Eikmanns, B.J.; Blombach, B.; Santos, H.
Stereospecificity of Corynebacterium glutamicum 2,3-butanediol dehydrogenase and implications for the stereochemical purity of bioproduced 2,3-butanediol
Appl. Microbiol. Biotechnol.
100
10573-10583
2016
Corynebacterium glutamicum
Manually annotated by BRENDA team
Li, L.; Zhang, L.; Li, K.; Wang, Y.; Gao, C.; Han, B.; Ma, C.; Xu, P.
A newly isolated Bacillus licheniformis strain thermophilically produces 2,3-butanediol, a platform and fuel bio-chemical
Biotechnol. Biofuels
6
123
2013
Bacillus licheniformis 10-1-A (X5F726), Bacillus licheniformis (X5F726)
Manually annotated by BRENDA team
Qi, G.; Kang, Y.; Li, L.; Xiao, A.; Zhang, S.; Wen, Z.; Xu, D.; Chen, S.
Deletion of meso-2,3-butanediol dehydrogenase gene budC for enhanced D-2,3-butanediol production in Bacillus licheniformis
Biotechnol. Biofuels
7
16
2014
Bacillus licheniformis, Bacillus licheniformis WX-02
Manually annotated by BRENDA team
Fu, J.; Huo, G.; Feng, L.; Mao, Y.; Wang, Z.; Ma, H.; Chen, T.; Zhao, X.
Metabolic engineering of Bacillus subtilis for chiral pure meso-2,3-butanediol production
Biotechnol. Biofuels
9
90
2016
Klebsiella pneumoniae, Klebsiella pneumoniae CICC10011
Manually annotated by BRENDA team
Guo, Z.; Zhao, X.; He, Y.; Yang, T.; Gao, H.; Li, G.; Chen, F.; Sun, M.; Lee, J.K.; Zhang, L.
Efficient (3R)-acetoin production from meso-2,3-butanediol using a new whole-cell biocatalyst with co-expression of meso-2,3-butanediol dehydrogenase, NADH oxidase and Vitreoscilla hemoglobin
J. Microbiol. Biotechnol.
27
92-100
2016
Serratia sp. (AEF50077), Serratia sp. T241 (AEF50077)
Manually annotated by BRENDA team
Kochius, S.; Paetzold, M.; Scholz, A.; Merkens, H.; Vogel, A.; Ansorge-Schumacher, M.; Hollmann, F.; Schrader, J.; Holtmann, D.
Enantioselective enzymatic synthesis of the alpha-hydroxy ketone (R)-acetoin from meso-2,3-butanediol
J. Mol. Catal. B
103
61-66
2014
uncultured bacterium
-
Manually annotated by BRENDA team
Hao, W.; Ji, F.; Wang, J.; Zhang, Y.; Wang, T.; Bao, Y.
Biochemical characterization of unusual meso-2,3-butanediol dehydrogenase from a strain of Bacillus subtilis
J. Mol. Catal. B
109
184-190
2014
Bacillus subtilis (A0A1D8FJM6), Klebsiella aerogenes (A0A0H3FZT7), Klebsiella aerogenes KCTC 2190 (A0A0H3FZT7)
-
Manually annotated by BRENDA team
Zhang, L.; Guo, Z.; Chen, J.; Xu, Q.; Lin, H.; Hu, K.; Guan, X.; Shen, Y.
Mechanism of 2,3-butanediol stereoisomers formation in a newly isolated Serratia sp. T241
Sci. Rep.
6
19257
2016
no activity in Escherichia coli
Manually annotated by BRENDA team