1.1.1.99: (S)-2-hydroxy-fatty-acid dehydrogenase

This is an abbreviated version, for detailed information about (S)-2-hydroxy-fatty-acid dehydrogenase, go to the full flat file.

Reaction

(S)-2-Hydroxystearate
+
NAD+
=
2-Oxostearate
+
NADH
+
H+

Synonyms

2-hydroxy fatty acid oxidase, dehydrogenase, L-2-hydroxy fatty acid, L-2-hydroxy fatty acid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.99 (S)-2-hydroxy-fatty-acid dehydrogenase

Cloned

Cloned on EC 1.1.1.99 - (S)-2-hydroxy-fatty-acid dehydrogenase

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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
three different genes, HAOX1, HAOX2, HAOX3, coding for 3 different 2-hydroxy acid oxidases, overexpression in Escherichia coli strain DH10B as His-tagged protein and in human skin fibroblasts GM5756-T cells as c-myc-tagged protein
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