1.1.1.95: phosphoglycerate dehydrogenase

This is an abbreviated version, for detailed information about phosphoglycerate dehydrogenase, go to the full flat file.

Reaction

3-phospho-D-glycerate
+
NAD+
=
3-phosphonooxypyruvate
+
NADH
+
H+

Synonyms

3-PGDH, 3-phosphoglycerate dehydrogenase, 3-phosphoglyceric acid dehydrogenase, 3PGDH, A10, alpha-phosphoglycerate dehydrogenase, ApPGDH, D-3-phosphoglycerate dehydrogenase, D-3-phosphoglycerate:NAD oxidoreductase, D-phosphoglycerate dehydrogenase, dehydrogenase, phosphoglycerate, EDA9, EhPGDH, glycerate 3-phosphate dehydrogenase, glycerate-1,3-phosphate dehydrogenase, More, NAD-dependent D-3-phosphoglycerate dehydrogenase, PGDH, PGDH1, PGDH2, PGDH3, PGK, Phgdh, phosphoglycerate dehydrogenase, phosphoglycerate kinase, phosphoglycerate oxidoreductase, phosphoglyceric acid dehydrogenase, serA, type 1 D-3-phosphoglycerate dehydrogenase, type III 3-phosphoglycerate dehydrogenase, type IIIK PGDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.95 phosphoglycerate dehydrogenase

Cloned

Cloned on EC 1.1.1.95 - phosphoglycerate dehydrogenase

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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
diverse mutants expressed in Escherichia coli
-
DNA and amino sequence analysis, phylogenetic analysis, sequence comparisons
-
DNA and amino sequence analysis, phylogenetic analysis, sequence comparisons, expression in Escherichia coli strain JM109
expressed in Escherichia coli
expressed in Escherichia coli and Arabidopsis thaliana
-
expressed in Escherichia coli BL-21 cells; expressed in Escherichia coli BL-21 cells; expressed in Escherichia coli BL-21 cells
expressed in Escherichia coli BL21 cells
expressed in Escherichia coli BL21(DE3) cells
expressed in HEK-293T cells
-
expression as selenomethionine-labeled enzyme in strain B834
-
expression in Escherichia coli
expression in Escherichia coli BL21
-
expression in Escheriochia coli BL21
expression of tagged wild-type and mutant enzymes
-
gene PHGDH consists of 12 exons and maps to chromosome 1p12, enzyme expression analysis in fibroblasts, transient overexpression of FLAG-tagged wild-type and mutant enzymes in HEK-293 cells
gene PHGDH, quantitative expression analysis in wild-type and mutant mice, genotyping, overview
-
gene serA, overexpression in Escherichia coli strains DH5alphaMCR and GM2929, co-overexpression of serA with other enzymes of the L-serine biosynthesis pathway leads to increased L-serine production in Corynebacterium glutamicum mutant serADELAT197
-
overexpression in Escherichia coli strain AD494 (DE3), cloning of GFP-mutant with transit peptide, expression in plant
-
overexpression of serA gene, that codes for the enzyme, in Escherichia coli strain JM105
-