188.8.131.52: homoisocitrate dehydrogenase
This is an abbreviated version, for detailed information about homoisocitrate dehydrogenase, go to the full flat file.
(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating), 2-hydroxy-3-carboxyadipate dehydrogenase, 3-carboxy-2-hydroxyadipate dehydrogenase, 3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating), dehydrogenase, homoisocitrate, EC 184.108.40.206, HIc, HIc dehydrogenase, HICDH, homoisocitrate dehydrogenase, homoisocitric dehydrogenase, isocitrate-homoisocitrate dehydrogenase, protein PH1722, ScHICDH
pH Range on EC 220.127.116.11 - homoisocitrate dehydrogenase
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5.5 - 9.5
pH independence of the catalytic reaction over the range of pH 5.5-9.5, pH profiles
6.1 - 7.7
pH 6.1: about 60% of activity maximum, pH 7.7: about 50% of activity maximum, reductive carboxylation
6.5 - 8.5
activity drops sharply below pH 6.5 and above pH 8.5
7.4 - 9.3
pH 7.4: about 50% of activity maximum, pH 9.3: about 90% of activity maximum, oxidative decarboxylation
pH-rate profile in the absence of K+, overview