1.1.1.83: D-malate dehydrogenase (decarboxylating)

This is an abbreviated version, for detailed information about D-malate dehydrogenase (decarboxylating), go to the full flat file.

Reaction

(R)-malate
+
NAD+
=
pyruvate
+
CO2
+
NADH

Synonyms

D-malate dehydrogenase, D-malic enzyme, dehydrogenase, D-malate (decarboxylating), dmlA

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.83 D-malate dehydrogenase (decarboxylating)

Temperature Stability

Temperature Stability on EC 1.1.1.83 - D-malate dehydrogenase (decarboxylating)

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30
-
half-life: 30 h
50
-
half-life: 120 min
55
-
half-life: 30 min
60
-
half-life: 9 min
65
-
2 min, 64% loss of activity
additional information
-
NAD+ provides better protection against inactivation than D-malate or beta,beta-dimethyl-DL-malate