1.1.1.83: D-malate dehydrogenase (decarboxylating)

This is an abbreviated version, for detailed information about D-malate dehydrogenase (decarboxylating), go to the full flat file.

Reaction

(R)-malate
+
NAD+
=
pyruvate
+
CO2
+
NADH

Synonyms

D-malate dehydrogenase, D-malic enzyme, dehydrogenase, D-malate (decarboxylating), dmlA

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.83 D-malate dehydrogenase (decarboxylating)

Inhibitors

Inhibitors on EC 1.1.1.83 - D-malate dehydrogenase (decarboxylating)

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,2-Butanedione
-
-
D-lactate
Dihydroxyfumarate
-
noncompetitive
iodoacetate
L-Tartrate
-
competitive with respect to D-malate
meso-tartrate
N-ethylmaleimide
-
1 mM, 18% inactivation
oxaloacetate
p-chloromercuribenzoate