1.1.1.8: glycerol-3-phosphate dehydrogenase (NAD+)

This is an abbreviated version, for detailed information about glycerol-3-phosphate dehydrogenase (NAD+), go to the full flat file.

Reaction

sn-glycerol 3-phosphate
+
acceptor
=
glycerone phosphate
+
reduced acceptor

Synonyms

(NAD+)-dependent G3pdh, (NAD+)-dependent glycerol-3-phosphate dehydrogenase, alpha glycerophosphate dehydrogenase, alpha-glycerol phosphate dehydrogenase (NAD), alpha-glycerophosphate dehydrogenase (NAD), Cagpd1, Cagpd2, cG3PDH, CgGPD, cGPdH, cytoplasmic NAD-dependent glycerol-3-phosphate dehydrogenase, dehydrogenase, glycerol phosphate, DhGPD1, G-3-P dehydrogenase, G3P dehydrogenase, G3PD, G3PDH, GDM, GDP2, GLPD, glycerol 1-phosphate dehydrogenase, glycerol 3-phosphate dehydrogenase, glycerol 3-phosphate dehydrogenase 1, glycerol phosphate dehydrogenase (NAD), glycerol-3-phosphate dehydrogenase, glycerol-3-phosphate dehydrogenase 1, glycerophosphate dehydrogenase (NAD), GPD, GPD1, GPDH, GPDH-1, GPDH-2, GPDH1, GPDH2, GPDH: NAD+ 2 oxidorreductase, GPDHc1, hydroglycerophosphate dehydrogenase, L-alpha-glycerol phosphate dehydrogenase, L-alpha-glycerophosphate dehydrogenase, L-glycerol 3-phosphate dehydrogenase, L-glycerol phosphate dehydrogenase, L-glycerophosphate dehydrogenase, mGPDH, NAD+-dependent glycerol 3-phosphate dehydrogenase, NAD+-dependent glycerol-3-phosphate dehydrogenase, NAD+-GPDH, NAD-alpha-glycerophosphate dehydrogenase, NAD-dependent cG3PDH, NAD-dependent glycerol phosphate dehydrogenase, NAD-dependent glycerol-3-phosphate dehydrogenase, NAD-L-glycerol-3-phosphate dehydrogenase, NAD-linked glycerol 3-phosphate dehydrogenase, NADH-dihydroxyacetone phosphate reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+)

Specific Activity

Specific Activity on EC 1.1.1.8 - glycerol-3-phosphate dehydrogenase (NAD+)

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.1
-
standard deviation 0.2, crude preparation, testes
33
-
isozyme P-V, liver
53.6
-
pH 7.6, 25C
55.6
-
pH 9.0, 25C
70.7
-
standard deviation 5.1, crude preparation, liver
77
-
isozyme I6.5, after affinity chromatography, after preparative isoelectric-focusing: 175 units/mg
80
-
estimated
88.2
-
-
96
-
isozyme P-I, liver
119
-
62 units/mg calculated by using protein concentration determined by dry-weight measurements
120
-
pH 7.5, 25C
123
-
isozyme P-IV, liver
156
-
isozyme GPDH-3
162
-
isozyme I5.9
170
-
standard deviation 45 units/mg
179.8
-
isozyme GPDH-1
180
-
mammary gland
234
-
adipose tissue,147 units/mg refer to protein determination by Kjeldahl nitrogen analysis
253
-
isozyme P-II, liver
257
-
purified enzyme, from liver, pH 8.5, 25C
282
-
purified enzyme, from muscle, pH 8.5, 25C
806
-
isozyme P-III, liver
2396
-
isoform Gut2, pH 6.8
additional information
-
activities with the different isozymes at different temperatures, overview