1.1.1.79: glyoxylate reductase (NADP+)

This is an abbreviated version, for detailed information about glyoxylate reductase (NADP+), go to the full flat file.

Reaction

glycolate
+
NADP+
=
glyoxylate
+
NADPH
+
H+

Synonyms

AtGR1, AtGR2, D-2-hydroxy-acid dehydrogenase, glyoxylate reductase, glyoxylate reductase 1, glyoxylate reductase 2, glyoxylate reductase isoform 1, glyoxylate reductase/hydroxypyruvate reductase, GLYR1, GLYR2, GOR1, GR/HPR, GR1, GR2, GRHPR, GRHRP, More, TthGR1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.79 glyoxylate reductase (NADP+)

Substrates Products

Substrates Products on EC 1.1.1.79 - glyoxylate reductase (NADP+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-oxoglutarate + NADH + H+
2-hydroxyglutarate + NAD+
show the reaction diagram
-
13.9% of glyoxylate activity
-
?
2-oxoisocaproate + NADPH + H+
2-hydroxy-4-methylpentanoate + NADP+
show the reaction diagram
acetaldehyde + NADPH + H+
ethanol + NADP+
show the reaction diagram
-
10.4% of glyoxylate activity
-
?
D-glycerate + NAD+
hydroxypyruvate + NADH + H+
show the reaction diagram
-
-
-
?
glycolate + NAD+
glyoxylate + NADH + H+
show the reaction diagram
-
-
-
r
glycolate + NADP+
glyoxylate + NADPH + H+
show the reaction diagram
-
-
-
r
glyoxal + NADPH
glycol + NADP+
show the reaction diagram
-
isoenzyme 1, 16% activity of glyxoxylate
-
?
glyoxylate + NAD(P)H
glycolate + NAD(P)+
show the reaction diagram
glyoxylate + NADH
glycolate + NAD+
show the reaction diagram
glyoxylate + NADH + H+
glycolate + NAD+
show the reaction diagram
glyoxylate + NADPH
glycolate + NADP+
show the reaction diagram
glyoxylate + NADPH + H+
glycolate + NADP+
show the reaction diagram
hydroxypyruvate + NAD(P)H
D-glycerate + NAD(P)+
show the reaction diagram
hydroxypyruvate + NAD(P)H
glycerate + NAD(P)+
show the reaction diagram
hydroxypyruvate + NADH
D-glycerate + NAD+
show the reaction diagram
-
affinity for NADPH is lower than affinity for NADH
-
-
?
hydroxypyruvate + NADH + H+
D-glycerate + NAD+
show the reaction diagram
-
-
-
-
?
hydroxypyruvate + NADPH
D-glycerate + NADP+
show the reaction diagram
-
-
-
-
?
hydroxypyruvate + NADPH + H+
D-glycerate + NADP+
show the reaction diagram
oxaloacetate + NADPH
malate + NADP+
show the reaction diagram
phenylpyruvate + NAD(P)H
phenyllactate + NAD(P)+
show the reaction diagram
-
isoenzyme 2, 6% activity of glyoxylate
-
?
succinic semialdehyde + NADH + H+
4-hydroxybutyrate + NAD+
show the reaction diagram
NADH much less effective than NADPH
-
-
?
succinic semialdehyde + NADPH + H+
4-hydroxybutyrate + NADP+
show the reaction diagram
additional information
?
-