1.1.1.79: glyoxylate reductase (NADP+)

This is an abbreviated version, for detailed information about glyoxylate reductase (NADP+), go to the full flat file.

Reaction

glycolate
+
NADP+
=
glyoxylate
+
NADPH
+
H+

Synonyms

AtGR1, AtGR2, D-2-hydroxy-acid dehydrogenase, glyoxylate reductase, glyoxylate reductase 1, glyoxylate reductase 2, glyoxylate reductase isoform 1, glyoxylate reductase/hydroxypyruvate reductase, GLYR1, GLYR2, GOR1, GR/HPR, GR1, GR2, GRHPR, GRHRP, More, TthGR1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.79 glyoxylate reductase (NADP+)

Disease

Disease on EC 1.1.1.79 - glyoxylate reductase (NADP+)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Carcinoma, Hepatocellular
Glyoxylate Reductase/Hydroxypyruvate Reductase: A Novel Prognostic Marker for Hepatocellular Carcinoma Patients after Curative Resection.
Colitis
Up regulation of glyoxylate reductase/hydroxypyruvate reductase (GRHPR) is associated with intestinal epithelial cells apoptosis in TNBS-induced experimental colitis.
glyoxylate reductase (nadp+) deficiency
[Primary hiperoxaluria: a new mutation in gen AGXT (R197Q) cause of neonatal convulsions]
Hyperoxaluria
[Primary hiperoxaluria: a new mutation in gen AGXT (R197Q) cause of neonatal convulsions]
Hyperoxaluria, Primary
Ethnic differences in GRHPR mutations in patients with primary hyperoxaluria type 2.
Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.
Up regulation of glyoxylate reductase/hydroxypyruvate reductase (GRHPR) is associated with intestinal epithelial cells apoptosis in TNBS-induced experimental colitis.
Kidney Calculi
Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.
Liver Cirrhosis
Association between angiotensin II type 1 receptor polymorphisms and the occurrence of nonalcoholic fatty liver disease.
Nephrocalcinosis
Hydroxyproline metabolism in mouse models of primary hyperoxaluria.
Non-alcoholic Fatty Liver Disease
Association between angiotensin II type 1 receptor polymorphisms and the occurrence of nonalcoholic fatty liver disease.
Obesity
Differential representation of liver proteins in obese human subjects suggests novel biomarkers and promising targets for drug development in obesity.