1.1.1.72: glycerol dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about glycerol dehydrogenase (NADP+), go to the full flat file.

Reaction

glycerol
+
NADP+
=
D-glyceraldehyde
+
NADPH
+
H+

Synonyms

AKR11B4, gamma-hydroxybutyrate dehydrogenase, glycerol dehydrogenase, GlyDH, Gox1615

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.72 glycerol dehydrogenase (NADP+)

Specific Activity

Specific Activity on EC 1.1.1.72 - glycerol dehydrogenase (NADP+)

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.259
-
during growth on wheat grains at water activity at the time of harvest 1.00
0.517
-
during growth on wheat grains at water activity at the time of harvest 0.97
0.582
-
during growth on wheat dough at water activity at the time of harvest 0.98
1.034
-
during growth on wheat dough at water activity at the time of harvest 0.96
4.2
W23A mutant protein, NADPH as variable substrate, pH 7.0, 30°C
4.9
W23A mutant protein, DL-glyceraldehyde as variable substrate, pH 7.0, 30°C
22.3
-
glyceraldehyde, crude extract of expressing Escherichia coli, pH not specified in the publication, temperature not specified in the publication
37
W23M mutant protein, DL-glyceraldehyde as variable substrate, pH 7.0, 30°C
54
W23M mutant protein, NADPH as variable substrate, pH 7.0, 30°C
80.5
wild-type protein, DL-glyceraldehyde as variable substrate, pH 7.0, 30°C
87.1
wild-type protein, NADPH as variable substrate, pH 7.0, 30°C
additional information
comparison of activity in the wild-type and two gldB disruption strains. The presence of 1 M NaCl results in a significant increase in activity in the wild-type strain. In the gldB disruptions hardly any activity is detected.