1.1.1.67: mannitol 2-dehydrogenase

This is an abbreviated version, for detailed information about mannitol 2-dehydrogenase, go to the full flat file.

Reaction

D-mannitol
+
NAD+
=
D-fructose
+
NADH
+
H+

Synonyms

D-mannitol dehydrogenase, DSF1, Hxt13, Hxt15, Hxt16, Hxt17, M2DH, Man1, MAN2, mannitol 2-dehydrogenase, mannitol dehydrogenase, mannitol dehydrogenase 1, mannitol dehydrogenase 2, mannitol transporter, mannitol-2-dehydrogenase, MDH, mt-dh, MtDH, MtlD, NAD+-dependent mannitol dehydrogenase, NADH-dependent mannitol dehydrogenase, pfMDH, polyol dehydrogenase, PsM2DH, TM0298, YNR073C

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.67 mannitol 2-dehydrogenase

Temperature Range

Temperature Range on EC 1.1.1.67 - mannitol 2-dehydrogenase

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TEMPERATURE RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
20 - 45
-
-
20 - 40
-
20C: about 85% of maximal activity, 40C: about 70% of maximal activity, reduction of D-fructose
20 - 50
about 40% activity at 20C, about 50% activity at 25C, about 70% activity at 30C, 100% activity at 35C, about 98% activity at 40C, about 90% activity at 45C, about 30% activity at 50C
80 - 95
-
more than 60% of the maximal activity between 80 and 95C
90 - 120
MtDH retains 63% of its activity at 120C but shows no detectable activity at 25C
95 - 120
retains 63% of its activity at 120C but shows no detectable activity at room temperature