1.1.1.64: testosterone 17beta-dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about testosterone 17beta-dehydrogenase (NADP+), go to the full flat file.

Reaction

testosterone
+
NADP+
=
androstenedione
+
NADPH
+
H+

Synonyms

17-ketoreductase, 17beta-HSD, 17beta-HSD 3, 17beta-HSD type 3, 17beta-HSD type 5, 17beta-HSD-3, 17beta-HSD1, 17beta-HSD3, 17beta-HSD4, 17beta-hydroxysteroid dehydrogenase, 17beta-hydroxysteroid dehydrogenase 3, 17beta-hydroxysteroid dehydrogenase type 3, 17beta-hydroxysteroid dehydrogenase type 5, 17beta-hydroxysteroid dehydrogenases type 3, 17betaHSD3, 3beta-hydroxysteroid dehydrogenase type 3, AKR1C3, More, NADP-dependent testosterone-17beta-oxidoreductase, type 3 17beta-HSD, type 3 17beta-hydroxysteroid dehydrogenase, type 5 beta-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)

Disease

Disease on EC 1.1.1.64 - testosterone 17beta-dehydrogenase (NADP+)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
3(or 17)beta-hydroxysteroid dehydrogenase deficiency
17beta-hydroxysteroid dehydrogenase type 3 deficiency as a result of a homozygous 7 base pair deletion in 17betaHSD3 gene.
46, XY Disorders of Sex Development
17Beta-hydroxysteroid dehydrogenase 3 deficiency in women.
17Beta-hydroxysteroid dehydrogenase-3 deficiency: diagnosis, phenotypic variability, population genetics, and worldwide distribution of ancient and de novo mutations.
Hypospadias
Genetic Polymorphisms of 17beta-Hydroxysteroid Dehydrogenase 3 and the Risk of Hypospadias.
testosterone 17beta-dehydrogenase (nadp+) deficiency
17beta-hydroxysteroid dehydrogenase 3 deficiency in a male pseudohermaphrodite.
17Beta-hydroxysteroid dehydrogenase 3 deficiency in women.
17beta-Hydroxysteroid dehydrogenase 3 deficiency.
17Beta-hydroxysteroid dehydrogenase-3 deficiency: diagnosis, phenotypic variability, population genetics, and worldwide distribution of ancient and de novo mutations.
17beta-Hydroxysteroid dehydrogenase-3 deficiency: from pregnancy to adolescence.
Clinical, endocrine, and molecular findings in 17beta-hydroxysteroid dehydrogenase type 3 deficiency.
Phenotypic variability in 17beta-hydroxysteroid dehydrogenase-3 deficiency and diagnostic pitfalls.