1.1.1.60: 2-hydroxy-3-oxopropionate reductase

This is an abbreviated version, for detailed information about 2-hydroxy-3-oxopropionate reductase, go to the full flat file.

Reaction

D-glycerate
+
NAD(P)+
=
2-hydroxy-3-oxopropanoate
+
NAD(P)H
+
H+

Synonyms

beta-hydroxyacid dehydrogenase, GarR, More, tartronate semialdehyde reductase, TSAR, TSR, TSR1, UM02592

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.60 2-hydroxy-3-oxopropionate reductase

Substrates Products

Substrates Products on EC 1.1.1.60 - 2-hydroxy-3-oxopropionate reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(R)-beta-hydroxybutyrate + NAD+
?
show the reaction diagram
-
-
-
-
?
(R)-glycerate + NAD(P)+
tartronate semialdehyde + NAD(P)H
show the reaction diagram
2-hydroxy-3-oxopropanoate + NADH + H+
D-glycerate + NAD+
show the reaction diagram
Q4PBC1
-
-
-
?
D-glycerate + NADP+
2-hydroxy-3-oxopropanoate + NADPH + H+
show the reaction diagram
Q4PBC1
enzyme shows strong specificity and enantioselectivity for D-glycerate
-
-
?
D-threonine + NAD+
?
show the reaction diagram
-
-
-
-
?
hydroxypyruvate + NAD(P)H
glycerate + NAD(P)+
show the reaction diagram
L-glycerate + NADP+
2-hydroxy-3-oxopropanoate + NADPH + H+
show the reaction diagram
Q4PBC1
enzyme shows strong specificity and enantioselectivity for D-glycerate
-
-
?
malonic semialdehyde + NADH
3-hydroxypropanoate + NAD+
show the reaction diagram
mesoxalic semialdehyde + NADH
hydroxypyruvate + NAD+
show the reaction diagram
tartronate semialdehyde + NAD(P)H
(R)-glycerate + NAD(P)+
show the reaction diagram
tartronate semialdehyde + NADH
(R)-glycerate + NAD+
show the reaction diagram
-
as cofactor in the final stage of D-glycerate biosynthesis
-
-
?
tartronate semialdehyde + NADH + H+
(R)-glycerate + NAD+
show the reaction diagram
-
-
-
-
?
additional information
?
-