1.1.1.59: 3-hydroxypropionate dehydrogenase

This is an abbreviated version, for detailed information about 3-hydroxypropionate dehydrogenase, go to the full flat file.

Reaction

3-hydroxypropanoate
+
NAD+
=
3-Oxopropanoate
+
NADH
+
H+

Synonyms

3-hydroxyisobutyrate dehydrogenase, Hpd1p

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.59 3-hydroxypropionate dehydrogenase

KM Value

KM Value on EC 1.1.1.59 - 3-hydroxypropionate dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.58
(R)-3-Hydroxyisobutyrate
at pH 9.5 and 22C
0.13
(S)-3-hydroxyisobutyrate
at pH 9.5 and 22C
5.37 - 20
3-hydroxypropanoate
16.8
3-hydroxypropionate
-
pH 8.5, 37C, KM-value for 3-hydroxyisobutyrate is approximately 20fold lower
46.7
L-serine
at pH 9.5 and 22C
0.34 - 2.4
NAD+
0.25
NADP+
-
pH 8.5, 37C
additional information
additional information
-
steady-state kinetic analysis, overview
-