1.1.1.54: allyl-alcohol dehydrogenase

This is an abbreviated version, for detailed information about allyl-alcohol dehydrogenase, go to the full flat file.

Reaction

allyl alcohol
+
NADP+
=
acrolein
+
NADPH
+
H+

Synonyms

ADH1, allyl-ADH, NtRed-1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.54 allyl-alcohol dehydrogenase

Engineering

Engineering on EC 1.1.1.54 - allyl-alcohol dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
isoform ADH1 oxidizes allyl alcohol to toxic acrolein. Use of the reaction to isolate mutations in the ADH1 gene that lead to decreased ADH activity. These yeast may grow more slowly due to slower reduction of acetaldehyde and a higher NADH/NAD+ ratio, which should decrease the oxidation of allyl alcohol