1.1.1.53: 3alpha(or 20beta)-hydroxysteroid dehydrogenase

This is an abbreviated version, for detailed information about 3alpha(or 20beta)-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

androstan-3alpha,17beta-diol
+
NAD+
=
17beta-hydroxyandrostan-3-one
+
NADH
+
H+

Synonyms

(R)-20-hydroxysteroid dehydrogenase, 20-hydroxysteroid dehydrogenase, 20beta-HSD, 20beta-HSD type 2, 20beta-hydroxysteroid dehydrogenase, 20HSD, 3-alpha hydroxysteroid dehydrogenase type 3, 3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase, 3alpha-HSD/CR, 3alpha-HSD3, 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase, carbonyl reductase-like 20beta-HSD, carbonyl reductase-like 20beta-hydroxysteroid dehydrogenase, carbonyl reductase/20beta-hydroxysteroid dehydrogenase A, carbonyl reductase/20beta-hydroxysteroid dehydrogenase B, cortisone reductase, CR/20beta-HSD, CR/20beta-HSD A, CR/20beta-HSD B, dehydrogenase, 20beta-hydroxy steroid, delta4-3-ketosteroid hydrogenase, NADH-20beta-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase

Molecular Weight

Molecular Weight on EC 1.1.1.53 - 3alpha(or 20beta)-hydroxysteroid dehydrogenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
23380
-
x * 23380, insertion protein, calculated from the deduced amino acid sequence, confirmed by SDS-PAGE
27000
-
4 * 27000, SDS-PAGE
28000
-
4 * 28000, about, crystal structure and sequence analysis
30000
-
SDS-PAGE
30140
x * 30140, isoform A, calculated from the deduced amino acid sequence
30500
-
gel filtration
106000 - 111000
-
agarose gel filtration, density gradient centrifugation