1.1.1.49: glucose-6-phosphate dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about glucose-6-phosphate dehydrogenase (NADP+), go to the full flat file.

Reaction

D-glucose 6-phosphate
+
NADP+
=
6-phospho-D-glucono-1,5-lactone
+
NADPH
+
H+

Synonyms

6-phosphoglucose dehydrogenase, beta-D-glucose-6-phosphate; NADP oxidoreductase, beta-D-glucose-6-phosphate;NADP oxido-reductase, D-glucose 6-phosphate dehydrogenase, D-glucose 6-phosphate: NADP+ oxidoreductase, D-glucose-6-phosphate: NADP+ oxidoreductase, D-glucose-6-phosphate:NADP oxidoreductase, Entner-Doudoroff enzyme, G-6-PD, G-6-PDH, G-6PD, G6PD, G6PD1, G6PD2, G6PD3, G6PD4, G6PD5, G6PD6, G6PDH, G6PDH-1, G6PDH-2, G6PDH1, G6PDH2, G6PDH3, G6PDH4, G6PDH5, G6PDH6, Glc6PDH, glucose 6-phosphate dehydrogenase, glucose 6-phosphate dehydrogenase (NADP), glucose-6-phosphate 1-dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, GPD, KlZWF1, NADP-dependent glucose 6-phophate dehydrogenase, NADP-glucose-6-phosphate dehydrogenase, P2-G6PDH, PfGluPho, plastidial glucose 6-phosphate dehydrogenase, VEG11, Vegetative protein 11, Zwf, zwf-1, Zwf-2, Zwischenferment

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)

Storage Stability

Storage Stability on EC 1.1.1.49 - glucose-6-phosphate dehydrogenase (NADP+)

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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-10°C, 10 mM Tris-HCl, pH 7.4, 5 mM 2-mercaptoethanol, 2 mM EDTA, 40% glycerol (v/v), weeks
-
-20°C or -40°C, impure state, more than 1 week
Penicillium duponti
-
-20°C, 0.05 M Tris-Cl buffer containing 1 mM glucose 6-phosphate, pH 7.5, stable for over 2 months
-
-20°C, 100 mM Tris-HCl buffer, pH 7.9, several months
30°C, Bacillus stearothermophilus enzyme maintains more than 80% of activity after 1 month
-
4°C, purified 650fold, several weeks
-
4°C, several months
4°C, storage in saline-adenine-glucose-mannitol, 6 weeks, the enzyme activity decreases significantly to 18%
-
5°C, pH 6.0-10.5, stable for 48 h
-