1.1.1.49: glucose-6-phosphate dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about glucose-6-phosphate dehydrogenase (NADP+), go to the full flat file.

Reaction

D-glucose 6-phosphate
+
NADP+
=
6-phospho-D-glucono-1,5-lactone
+
NADPH
+
H+

Synonyms

6-phosphoglucose dehydrogenase, D-glucose 6-phosphate dehydrogenase, D-glucose 6-phosphate: NADP+ oxidoreductase, D-glucose-6-phosphate: NADP+ oxidoreductase, D-glucose-6-phosphate:NADP oxidoreductase, Entner-Doudoroff enzyme, G-6-PD, G-6-PDH, G-6PD, G6PD, G6PD1, G6PD2, G6PD3, G6PD4, G6PD5, G6PD6, G6PDH, G6PDH-1, G6PDH-2, G6PDH1, G6PDH2, G6PDH3, G6PDH4, G6PDH5, G6PDH6, Glc6PDH, glucose 6-phosphate dehydrogenase, glucose 6-phosphate dehydrogenase (NADP), glucose-6-phosphate 1-dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, GPD, KlZWF1, NADP-dependent glucose 6-phophate dehydrogenase, NADP-glucose-6-phosphate dehydrogenase, PfGluPho, VEG11, Vegetative protein 11, Zwischenferment

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)

Molecular Weight

Molecular Weight on EC 1.1.1.49 - glucose-6-phosphate dehydrogenase (NADP+)

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10000
-
dimeric apoenzyme, gel filtration
31000
-
4 * 31000, SDS-PAGE
35200
-
4 * 35200, G6PDH-1, SDS-PAGE
48000
-
4 * 48000, SDS-PAGE
48500
-
x * 48500, SDS-PAGE
52500
-
2 * 52500, SDS-PAGE
53100
-
x * 53100, SDS-PAGE
54000
-
2 * 54000, SDS-PAGE
55300
-
2 * 55300, SDS-PAGE
56000
-
? * 56000, SDS-PAGE
57500
-
about, recombinant enzyme, native PAGE
58000
-
2 * 58000, SDS gel electrophoresis
59000
-
? * 59000, SDS-PAGE, native and recombinant from Escherichia coli
59500
-
x * 59500, calculated from sequence
63000
x * 63000, SDS-PAGE
65000
-
4 * 65000, Zwischenferment
66880
-
2 * 66880, SDS-PAGE
68000
-
2 * 68000, SDS-PAGE
68400
-
4 * 68400, SDS-PAGE
73200
-
gel filtration
77600
-
gel filtration
95000
-
gel filtration, recombinant enzyme
100000
-
gel filtration, refolded protein
103000 - 110000
105000
-
gel filtration
110000
-
G6PDH-2, gel filtration
112000
-
gel filtration
114000
-
dimer dimerization to MW 209000 in presence of NADP+, gel filtration
117000
-
gel filtration
118000 - 120000
120000
-
gel filtration
121000
-
gel filtration
126000
Penicillium duponti
-
gel filtration
130000
-
G6PDH-1, gel filtration
134000
-
gel filtration
138000
-
gel filtration
144000
-
gel filtration
150000
-
gel filtration
158000
-
gel filtration
160000
-
gel filtration
180000
200000
206000
-
gel electrophoresis
210000
-
-
220000
238700
-
ultracentrifugation
240000
265000
-
Zwischenferment, gel chromatography
300000
-
recombinant His-tagged enzyme, gel filtration
345000
-
three principal forms with MW of 120000 Da, 240000 Da and 345000 Da, gel electrophoresis
additional information
-
native PAGE