1.1.1.49: glucose-6-phosphate dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about glucose-6-phosphate dehydrogenase (NADP+), go to the full flat file.

Reaction

D-glucose 6-phosphate
+
NADP+
=
6-phospho-D-glucono-1,5-lactone
+
NADPH
+
H+

Synonyms

6-phosphoglucose dehydrogenase, D-glucose 6-phosphate dehydrogenase, D-glucose 6-phosphate: NADP+ oxidoreductase, D-glucose-6-phosphate: NADP+ oxidoreductase, D-glucose-6-phosphate:NADP oxidoreductase, Entner-Doudoroff enzyme, G-6-PD, G-6-PDH, G-6PD, G6PD, G6PD1, G6PD2, G6PD3, G6PD4, G6PD5, G6PD6, G6PDH, G6PDH-1, G6PDH-2, G6PDH1, G6PDH2, G6PDH3, G6PDH4, G6PDH5, G6PDH6, Glc6PDH, glucose 6-phosphate dehydrogenase, glucose 6-phosphate dehydrogenase (NADP), glucose-6-phosphate 1-dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, GPD, KlZWF1, NADP-dependent glucose 6-phophate dehydrogenase, NADP-glucose-6-phosphate dehydrogenase, PfGluPho, VEG11, Vegetative protein 11, Zwischenferment

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)

KI Value

KI Value on EC 1.1.1.49 - glucose-6-phosphate dehydrogenase (NADP+)

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
12.25
(((6-(4-tolyl)thieno[2,3-d]pyrimidin-4-yl)amino)methylene)diphosphonic acid
-
pH 8.0, 25C
-
0.0048
5alpha-Androstan-3beta-ol-17-one
-
substrate D-glucose 6-phosphate, pH 7.6, temperature not specified in the publication; substrate NADP+, pH 7.6, temperature not specified in the publication
0.0136
6-phosphogluconate
-
Kis, variable substrate D-glucose 6-phosphate
0.00226
ammonia
-
-
643.5
amoxicillin
Chalcalburnus tarischii
-
25C, pH 8.5
6.5 - 16.61
ATP
2.034
Cd2+
-
pH 6.0, 25C
2.26
Ciprofloxacin
Chalcalburnus tarischii
-
25C, pH 8.5
0.0047
Co2+
-
pH 7.5
1.721
Cu2+
-
pH 6.0, 25C
2.63
cypermethrin
-
-
0.1053
D-glucose 6-phosphate
-
pH 7.6, temperature not specified in the publication
0.0215 - 0.0223
dehydroandrosterone
0.0011 - 0.0017
dehydroepiandrosterone
1.84
deltamethrin
-
-
0.00046 - 0.00049
epiandrosterone
0.197
Fe2+
-
pH 6.0, 25C
0.308
gentamicin sulfate
-
pH 8.0, 25C
13.8 - 35.1
glucosamine 6-phosphate
0.542
Hg2+
-
pH 6.0, 25C
0.0002
KMnO4
Chalcalburnus tarischii
-
25C, pH 8.5
0.0446
marcaine
-
-
0.392
metamizol
-
-
12.12
MgSO4
-
-
0.112
NADH
-
pH 8.0, 25C
0.023
NADP+
-
pH 7.5
0.00195 - 2.09
NADPH
1.178
nidazole
Chalcalburnus tarischii
-
25C, pH 8.5
0.213
Pb2+
-
pH 6.0, 25C
0.748
penicillin G potassium
-
pH 8.0, 25C
0.748
pental sodium
-
-
16.55
propoxur
-
-
0.032
sulfanilacetamide
Chalcalburnus tarischii
-
25C, pH 8.5
0.037
sulfanilamide
Chalcalburnus tarischii
-
25C, pH 8.5
0.00186
Urea
-
-
1.466 - 1.88
Vancomycin
0.0066 - 2.77
Zn2+
additional information
additional information
-
-
-