1.1.1.45: L-gulonate 3-dehydrogenase

This is an abbreviated version, for detailed information about L-gulonate 3-dehydrogenase, go to the full flat file.

Reaction

L-gulonate
+
NAD+
=
3-dehydro-L-gulonate
+
NADH
+
H+

Synonyms

GDH, L-3-aldonate dehydrogenase, L-3-aldonic dehydrogenase, L-3-hydroxyacid dehydrogenase, L-beta-hydroxy-acid-NAD-oxidoreductase, L-beta-hydroxyacid dehydrogenase, L-gulonate 3-dehydrogenase, L-gulonic acid dehydrogenase, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.45 L-gulonate 3-dehydrogenase

Inhibitors

Inhibitors on EC 1.1.1.45 - L-gulonate 3-dehydrogenase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
acetoacetate
-
competitive inhibitor
Cibacron blue
-
competitive inhibition with respect to NAD+
malonate
-
reversible inhibition, IC50: 0.34 mM
malonic acid monoethyl ester
-
weak inhibition, IC50: 5.5 mM
NADH
-
competitive inhibitor
p-chloromercuribenzoate
p-Chloromercuriphenylsulfonate
-
0.001 mM, complete inhibition
Phenylmercurinitrate
-
-
additional information
-