1.1.1.44: phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)

This is an abbreviated version, for detailed information about phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating), go to the full flat file.

Reaction

6-phospho-D-gluconate
+
NADP+
=
D-ribulose 5-phosphate
+
CO2
+
NADPH
+
H+

Synonyms

6-GPD, 6-P-gluconate dehydrogenase, 6-Pgd, 6-PGDH, 6-PGDHase, 6-phospho-D-gluconate dehydrogenase, 6-phospho-D-gluconate-NADP+ oxidoreductase, decarboxylating, 6-phosphogluconate dehydrogenase, 6-phosphogluconate dehydrogenase (decarboxylating), 6-phosphogluconate dehydrogenase Gnd1, 6-phosphogluconate dehydrogenase, decarboxylating, 6-phosphogluconate-dehydrogenase, 6-phosphogluconate:NADP oxidoreductase, 6-phosphogluconic carboxylase, 6-phosphogluconic dehydrogenase, 6-phosphonogluconate dehydrogenase, 6PDH, 6PG DH, 6PGD, 6PGDH, 6PGDH/Gnd1, D-gluconate-6-phosphate dehydrogenase, gnd, GND1, GNTZII, LlPDH, Os6PGDH2, phosphogluconic acid dehydrogenase, YpjI

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)

Molecular Weight

Molecular Weight on EC 1.1.1.44 - phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30000
-
2 * 30000, SDS-PAGE
38000
-
4 * 38000, SDS-PAGE
45000
-
1 * 49000 + 1 * 45000, SDS-PAGE
47000
-
2 * 47000, SDS-PAGE
49000
-
1 * 49000 + 1 * 45000, SDS-PAGE
51400
2 * 51980, sequence determination, 2 * 51400, recombinant enzyme, SDS-PAGE
51980
2 * 51980, sequence determination, 2 * 51400, recombinant enzyme, SDS-PAGE
52400
x * 52400, calculated from sequence
53000
-
SDS-PAGE
53400
-
SDS-PAGE, HAT-tagged r6PGD fusion protein
55000
-
2 * 55000, SDS-PAGE
58000
-
2 * 58000, SDS-PAGE
63000
-
x * 63000, alternatively spliced Gnd1-3xHA isoform, SDS-PAGE
69000 - 72000
-
2 isoenzymes, gel filtration
79000
-
gel filtration of haemolysates
83000
-
gel filtration, method of Ornstein and Davis
90000
-
gel filtration, Bio-Gel 200
92000
-
gel filtration, PAGE
93000
recombinant enzyme, gel filtration
95000
-
gel filtration
98000
-
sedimentation equilibrium
101000
102000
106000 - 115000
108000
110000 - 120000
110000
111000
129000
158000
-
gel filtration
229000
-
gel filtration