1.1.1.40: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)

This is an abbreviated version, for detailed information about malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+), go to the full flat file.

Reaction

(S)-malate
+
NADP+
=
pyruvate
+
CO2
+
NADPH

Synonyms

ADP-malic enzyme2, c-NADP-ME, C4 NADP-malic enzyme, C4 photosynthetic NADP-malic enzyme, C4-NADP-malic enzyme, C4-NADP-ME, ChlME1, ChlME2, cytoNADPME, cytosolic malic enzyme, cytosolic NADP+-dependent isoform, cytosolic NADP+-dependent malic enzyme, L-malate: NADP oxidoreductase (decarboxylating), L-malate: NADP oxidoreductase [OAA decarboxylating], L-malate: NADP oxidoreductase [oxaloacetate decarboxylating], L-malate:NADP oxidoreductase, L-malate:NADP oxidoreductase (oxaloacetate decarboxylating), MaeB, MalA, malate dehydrogenase (decarboxylating, NADP), malate dehydrogenase (NADP, decarboxylating), malE1, malic enzyme, malic enzyme 1, malic enzyme 3, malic enzyme-NADP, ME, ME-NADP, ME1, ME2, ME3, NAD(P)+-malic enzyme, NADP dependent malic enzyme, NADP malic enzyme, NADP+ dependent malic enzyme, NADP+-dependent malic enzyme, NADP+-dependent malic enzyme 3, NADP+-ME, NADP-dependent malate dehydrogenase, NADP-dependent malic enzyme, NADP-linked decarboxylating malic enzyme, NADP-malate enzyme, NADP-malic enzyme, NADP-malic enzyme 2, NADP-MDH, NADP-ME, NADP-ME1, NADP-ME2, NADP-ME3, NADP-ME4, NADP-specific malate dehydrogenase, NADP-specific malic enzyme, NADP-specific ME, pyruvic-malic carboxylase, TME

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)

Specific Activity

Specific Activity on EC 1.1.1.40 - malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.008 - 0.89
-
enzyme activity in several recombinant strains, overview
0.01
-
below, wild-type strain W3110
0.048
enzyme extracts from flowers; enzyme extracts from flowers
0.069
enzyme extracts from stems; enzyme extracts from stems
0.072
enzyme extracts from leaves; enzyme extracts from leaves
0.16
root enzyme under salt stress after 24 h
0.2
leaf enzyme under salt stress after 24 h
0.571
enzyme extract from roots; enzyme extract from roots
1.69
-
MaeB overexpressed in an anaplerotic enzyme overexpressing strain
1.92
-
recombinant enzyme in INS-1 832/13 cells, reverse reaction, pH 7.4, temperature not specified in the publication
3.15
pH 7.8, 46°C, purified recombinant enzyme
5.04
-
-
18.2
-
purified enzyme
30.14
-
partially purified leaf isozyme 2
36.6
-
60°C, pH 8.0
56.35
-
-
78.6
recombinant NADP-ME3
85.1
recombinant NADP-ME2
90.9
-
mitochondrial enzyme
91.4
-
cytosolic enzyme
199
purified enzyme
additional information