1.1.1.4: (R,R)-butanediol dehydrogenase

This is an abbreviated version, for detailed information about (R,R)-butanediol dehydrogenase, go to the full flat file.

Reaction

(R,R)-butane-2,3-diol
+
NAD+
=
(R)-acetoin
+
NADH
+
H+

Synonyms

(2R,3R)-2,3-butanediol dehydrogenase, (R)-2,3-butanediol dehydrogenase, (R)-diacetyl reductase, 1-amino-2-propanol dehydrogenase, 1-amino-2-propanol oxidoreductase, 2,3-BDH/AR, 2,3-butanediol dehydrogenase, 2,3-butanediol dehydrogenase/acetoin reductase, 2R,3R-2,3-BD dehydrogenase, 2R-3R-BDH, acetoin reductase, ADH-9, aminopropanol oxidoreductase, AR/BDH, BDH, BDH1, BDH99::67, BdhA, ButA, butylene glycol dehydrogenase, butyleneglycol dehydrogenase, D-(-)-butanediol dehydrogenase, D-1-amino-2-propanol dehydrogenase, D-1-amino-2-propanol:NAD+ oxidoreductase, D-2,3-BD dehydrogenase, D-aminopropanol dehydrogenase, dehydrogenase, D-aminopropanol, dehydrogenase, D-butanediol, DHAD, diacetyl reductase (acetoin), EC 1.1.1.74, GDH, GldA, meso-2,3-butanediol dehydrogenase, meso-BDH, NAD(H)-dependent 2,3-butanediol dehydrogenase, NADH-dependent 2,3-butanediol dehydrogenase, R,R-BD-DH, R,R-BDH, SLAC

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.4 (R,R)-butanediol dehydrogenase

KM Value

KM Value on EC 1.1.1.4 - (R,R)-butanediol dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
14 - 65
(2R,3R)-2,3-butanediol
0.58 - 236.4
(2R,3R)-butane-2,3-diol
0.23
(2S)-acetoin
-
at pH 10.5 and 30C
-
0.052
(2S,3S)-butane-2,3-diol
-
at pH 10.5 and 30C
0.06 - 4.5
(3R,3S)-acetoin
4.15 - 12.06
(3R,3S)-butane-2,3-diol
-
0.12 - 230
(R)-acetoin
2.01 - 6.01
(R,R)-butane-2,3-diol
38
1,2-propanediol
-
-
14.5
1-hydroxy-2-propanone
-
-
2.6 - 86.8
2,3-Butanediol
6
2,3-pentanediol
-
-
0.8 - 3.6
2-butanone
5.5
acetaldehyde
-
pH 7.5, 25C
0.4 - 71
acetoin
0.6 - 2
acetone
1.2
Butanone
-
pH 7.5, 25C
3.3
D-(-)2,3-butanediol
-
-
0.1 - 87
diacetyl
20
ethyl pyruvate
-
-
14.49 - 93.62
glycerol
6.25
meso-2,3-butanediol
-
-
2.73 - 37.39
meso-butane-2,3-diol
75
methyl glyoxal
-
-
18
Methyl pyruvate
-
-
0.16 - 2.3
NAD+
0.045 - 0.7
NADH
0.0017 - 0.087
NADPH