1.1.1.4: (R,R)-butanediol dehydrogenase

This is an abbreviated version, for detailed information about (R,R)-butanediol dehydrogenase, go to the full flat file.

Reaction

(R,R)-butane-2,3-diol
+
NAD+
=
(R)-acetoin
+
NADH
+
H+

Synonyms

(2R,3R)-2,3-butanediol dehydrogenase, (R)-2,3-butanediol dehydrogenase, (R)-diacetyl reductase, 1-amino-2-propanol dehydrogenase, 1-amino-2-propanol oxidoreductase, 2,3-BDH/AR, 2,3-butanediol dehydrogenase, 2,3-butanediol dehydrogenase/acetoin reductase, 2R,3R-2,3-BD dehydrogenase, 2R-3R-BDH, acetoin reductase, ADH-9, aminopropanol oxidoreductase, AR/BDH, BDH, BDH1, BDH99::67, BdhA, ButA, butylene glycol dehydrogenase, butyleneglycol dehydrogenase, D-(-)-butanediol dehydrogenase, D-1-amino-2-propanol dehydrogenase, D-1-amino-2-propanol:NAD+ oxidoreductase, D-2,3-BD dehydrogenase, D-aminopropanol dehydrogenase, dehydrogenase, D-aminopropanol, dehydrogenase, D-butanediol, DHAD, diacetyl reductase (acetoin), EC 1.1.1.74, GDH, GldA, meso-2,3-butanediol dehydrogenase, meso-BDH, NAD(H)-dependent 2,3-butanediol dehydrogenase, NADH-dependent 2,3-butanediol dehydrogenase, R,R-BD-DH, R,R-BDH, SLAC

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.4 (R,R)-butanediol dehydrogenase

KCat KM Value

KCat KM Value on EC 1.1.1.4 - (R,R)-butanediol dehydrogenase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.033
(2R,3R)-2,3-butanediol
Clostridium autoethanogenum
-
pH 7.5, 25C
16548
0.03 - 7.379
(2R,3R)-butane-2,3-diol
14490
221.2
(2S)-acetoin
Corynebacterium glutamicum
-
at pH 10.5 and 30C
213971
187.5
(2S,3S)-butane-2,3-diol
Corynebacterium glutamicum
-
at pH 10.5 and 30C
81773
0.31 - 2.51
(3R,3S)-butane-2,3-diol
213970
0.35 - 2.8
(R)-acetoin
4876
0.9
(R,R)-butane-2,3-diol
Corynebacterium glutamicum
-
at pH 10.5 and 30C
44987
7.8 - 61
2-butanone
1171
17
acetaldehyde
Clostridium autoethanogenum
-
pH 7.5, 25C
90
2
acetoin
Clostridium autoethanogenum
-
pH 7.5, 25C
1274
24 - 86
acetone
333
38
Butanone
Clostridium autoethanogenum
-
pH 7.5, 25C
3620
61.1
diacetyl
Rhodococcus erythropolis
A0A0E4A9D6
at pH 10.0 and 45C
746
0.11 - 1.3
glycerol
135
0.13 - 3.11
meso-butane-2,3-diol
42410
9.875
NAD+
Rhodococcus erythropolis
A0A0E4A9D6
with (2R,3R)-butane-2,3-diol as cosubstrate, at pH 6.5 and 55C
7
71.63
NADH
Rhodococcus erythropolis
A0A0E4A9D6
with diacetyl as cosubstrate, at pH 10.0 and 45C
8
890 - 39000
NADPH
5