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1.1.1.391: 3beta-hydroxycholanate 3-dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about 3beta-hydroxycholanate 3-dehydrogenase (NAD+), go to the full flat file.

Reaction

isolithocholate
+
NAD+
=
3-oxo-5beta-cholan-24-oate
+
NADH
+
H+

Synonyms

3beta-HSD, 3beta-HSDH, 3beta-hydroxysteroid dehydrogenase, bile acid 3beta-HSD, iso bile acid dehydrogenase, NAD-dependent 3beta-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.391 3beta-hydroxycholanate 3-dehydrogenase (NAD+)

KM Value

KM Value on EC 1.1.1.391 - 3beta-hydroxycholanate 3-dehydrogenase (NAD+)

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2.63 - 2.66
12alpha-hydroxy-3-oxo-5-beta-cholan-24-oic acid
0.0153
3beta,7alpha-dihydroxy-5beta-cholan-24-oic acid
-
pH 7.5, 25°C, recombinant enzyme
0.0238
3beta,7beta-dihydroxy-5beta-cholan-24-oic acid
-
pH 7.5, 25°C, recombinant enzyme
0.0183 - 0.0283
3beta-hydroxy-5beta-cholan-24-oic acid
additional information
additional information
-
Michaelis-Menten kinetis
-