1.1.1.39: malate dehydrogenase (decarboxylating)

This is an abbreviated version, for detailed information about malate dehydrogenase (decarboxylating), go to the full flat file.

Reaction

(S)-malate
+
NAD+
=
pyruvate
+
CO2
+
NADH

Synonyms

AZC3656 protein, dehydrogenase, malate, diphosphate nucleotide dependent malic enzyme, DMA, DME, m-NAD-ME, malic enzyme, malic enzyme 2, malic enzyme-NAD, ME, ME-NAD, ME2, mitochondrial malic enzyme, mitochondrial NAD(P)+-dependent malic enzyme, mitochondrial NAD+-dependent malic enzyme, mitochondrial NAD-malic enzyme, NAD(P)+-malic enzyme, NAD+-dependent malic enzyme, NAD-dependent malic enzyme, NAD-malic enzyme, NAD-ME, NAD-ME1, NAD-ME2, NAD-MEH, NAD-preferring malic enzyme, NAD-preferring ME, NAD-specific malic enzyme, pyruvic-malic carboxylase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.39 malate dehydrogenase (decarboxylating)

Substrates Products

Substrates Products on EC 1.1.1.39 - malate dehydrogenase (decarboxylating)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2R,3R)-erythrofluoromalate + NAD+
?
show the reaction diagram
-
-
-
-
?
(2S,3R)-tartrate + NAD+
?
show the reaction diagram
-
-
-
-
?
(S)-malate + NAD(P)+
pyruvate + CO2 + NAD(P)H
show the reaction diagram
(S)-malate + NAD+
?
show the reaction diagram
(S)-malate + NAD+
pyruvate + CO2 + NADH
show the reaction diagram
(S)-malate + NAD+
pyruvate + NADH + CO2
show the reaction diagram
-
-
-
-
ir
(S)-malate + NAD+
pyruvate + NADH + H+ + CO2
show the reaction diagram
(S)-malate + NADP+
pyruvate + CO2 + NADPH
show the reaction diagram
(S)-malate + NADP+
pyruvate + NADPH + H+ + CO2
show the reaction diagram
L-aspartate + NAD+
iminopyruvate + CO2 + NADH
show the reaction diagram
-
-
-
-
?
L-malate + NAD+
pyruvate + NADH + H+ + CO2
show the reaction diagram
-
-
-
-
r
malate + NAD+
pyruvate + CO2 + NADH
show the reaction diagram
meso-tartrate + NAD+
?
show the reaction diagram
-
-
-
-
?
pyruvate + CO2 + NADH
(S)-malate + NAD+
show the reaction diagram
Crassula argentea
-
activity is 1.5% of the decarboxylation of (S)-malate
-
r
pyruvate + NAD+ + HCO3-
(S)-malate + NADH
show the reaction diagram
additional information
?
-