1.1.1.39: malate dehydrogenase (decarboxylating)

This is an abbreviated version, for detailed information about malate dehydrogenase (decarboxylating), go to the full flat file.

Reaction

(S)-malate
+
NAD+
=
pyruvate
+
CO2
+
NADH

Synonyms

AZC3656 protein, dehydrogenase, malate, diphosphate nucleotide dependent malic enzyme, DMA, DME, m-NAD-ME, malic enzyme, malic enzyme 2, malic enzyme-NAD, ME, ME-NAD, ME2, mitochondrial malic enzyme, mitochondrial NAD(P)+-dependent malic enzyme, mitochondrial NAD+-dependent malic enzyme, mitochondrial NAD-malic enzyme, NAD(P)+-malic enzyme, NAD+-dependent malic enzyme, NAD-dependent malic enzyme, NAD-malic enzyme, NAD-ME, NAD-ME1, NAD-ME2, NAD-MEH, NAD-preferring malic enzyme, NAD-preferring ME, NAD-specific malic enzyme, pyruvic-malic carboxylase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.39 malate dehydrogenase (decarboxylating)

KI Value

KI Value on EC 1.1.1.39 - malate dehydrogenase (decarboxylating)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.45 - 1.5
5'-AMP
3 - 7
CO2
7.4
fructose 6-phosphate
pH 7.2, 30°C, versus (S)-malate
58 - 80
L-aspartate
0.0048 - 0.148
Lu3+
0.041 - 0.15
NADH
0.006
oxalate
-
pH 7.0, 25°C, recombinant wild-type enzyme
0.36
oxaloacetate
pH 7.2, 30°C, versus (S)-malate
11 - 14
pyruvate
0.8 - 4
Tartrate
additional information
additional information
-