1.1.1.37: malate dehydrogenase

This is an abbreviated version, for detailed information about malate dehydrogenase, go to the full flat file.

Reaction

(S)-malate
+
NAD+
=
oxaloacetate
+
NADH
+
H+

Synonyms

(R)-2-hydroxyacid dehydrogenase, (S)-malate dehydrogenase, CaMDH, cMDH, cMDH -S, cMDH-L, cyMDH, cytosolic malate dehydrogenase, cytosolic MDH, cytosolic NAD-dependent malate dehydrogenase, halophilic malate dehydrogenase, HmMalDH, L-malate dehydrogenase, L-malate-NAD oxidoreductase, L-malate: NAD oxidoreductase, L-malate: NAD+ oxidoreductase, L-malate:NAD-oxidoreductase, L-MDH, m-MDH, malate (NAD) dehydrogenase, malate dehydrogenase, malate dehydrogenase (NAD), malate dehydrogenase 1, malate dehydrogenase 2, malate: NAD oxidoreductase, MalDH, malic acid dehydrogenase, malic dehydrogenase, mbNAD-MDH, MDH, MDH A, MDH B1, MDH B2, Mdh1, MDH2, Mdh2a, Mdh2b, mitochondrial malate dehydrogenase, mitochondrial MDH, mMDH, mNAD-MDH, More, NAD+-dependent malate dehydrogenase, NAD+-dependent MDH, NAD+-MDH enzymes, NAD-dependent malate dehydrogenase, NAD-dependent malic dehydrogenase, NAD-dependent MDH, NAD-L-malate dehydrogenase, NAD-linked malate dehydrogenase, NAD-malate dehydrogenase, NAD-malic dehydrogenase, NAD-MDH, NAD-specific malate dehydrogenase, Pcal_1699, peroxisomal NAD+-malate dehydrogenase 1, peroxisomal NAD+-malate dehydrogenase 2, PMDH, PMDH1, PMDH2, regulatory subunit of nucleic acid-conducting channel, s-MDH, SrMalDH, TaMDH, VEG69, Vegetative protein 69, YlMdh2p, [LDH-like] MDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.37 malate dehydrogenase

pI Value

pI Value on EC 1.1.1.37 - malate dehydrogenase

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pI VALUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3.5
-
the isoform with a pI of 3.5 appears exclusively in the purified plasma membrane isolate, isoelectric focusing
4.5
isoelectric focusing, pH 3–10
4.6
-
the remaining soluble isoforms being mainly acidic show a pI between 4 and 5, amongst the acidic isoforms, the most prominent has a pI of around 4.6, isoelectric focusing
5.3
-
the stromal fraction of the chloroplasts contain one isoform with a pI value around 5.3, isoelectric focusing
5.4
2-dimensional electrophoresis, recombinant enzyme
5.75
-
plasma membrane-associated enzyme, sequence calculation
5.9
-
mitochondrial MDH, calculated from amino acid sequence
6
-
denaturing isoelectric focusing
6.2
-
cytosolic MDH, calculated from amino acid sequence
6.8
-
purified recombinant enzyme, isoelectric focussing
8.1
calculated and isoelectric focusing; isoelectrofocusing
9
-
most abundant soluble isoform, isoelectric focusing
9.7
-
isoelectric focusing