1.1.1.37: malate dehydrogenase

This is an abbreviated version, for detailed information about malate dehydrogenase, go to the full flat file.

Reaction

(S)-malate
+
NAD+
=
oxaloacetate
+
NADH
+
H+

Synonyms

(R)-2-hydroxyacid dehydrogenase, (S)-malate dehydrogenase, CaMDH, cMDH, cMDH -S, cMDH-L, cyMDH, cytosolic malate dehydrogenase, cytosolic MDH, cytosolic NAD-dependent malate dehydrogenase, halophilic malate dehydrogenase, HmMalDH, L-malate dehydrogenase, L-malate-NAD oxidoreductase, L-malate: NAD oxidoreductase, L-malate: NAD+ oxidoreductase, L-malate:NAD-oxidoreductase, L-MDH, m-MDH, malate (NAD) dehydrogenase, malate dehydrogenase, malate dehydrogenase (NAD), malate dehydrogenase 1, malate dehydrogenase 2, malate: NAD oxidoreductase, MalDH, malic acid dehydrogenase, malic dehydrogenase, mbNAD-MDH, MDH, MDH A, MDH B1, MDH B2, Mdh1, MDH2, Mdh2a, Mdh2b, mitochondrial malate dehydrogenase, mitochondrial MDH, mMDH, mNAD-MDH, More, NAD+-dependent malate dehydrogenase, NAD+-dependent MDH, NAD+-MDH enzymes, NAD-dependent malate dehydrogenase, NAD-dependent malic dehydrogenase, NAD-dependent MDH, NAD-L-malate dehydrogenase, NAD-linked malate dehydrogenase, NAD-malate dehydrogenase, NAD-malic dehydrogenase, NAD-MDH, NAD-specific malate dehydrogenase, Pcal_1699, peroxisomal NAD+-malate dehydrogenase 1, peroxisomal NAD+-malate dehydrogenase 2, PMDH, PMDH1, PMDH2, regulatory subunit of nucleic acid-conducting channel, s-MDH, SrMalDH, TaMDH, VEG69, Vegetative protein 69, YlMdh2p, [LDH-like] MDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.37 malate dehydrogenase

Molecular Weight

Molecular Weight on EC 1.1.1.37 - malate dehydrogenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
21550
-
4 * 21550, SDS-PAGE
27500
-
2 * 27500, SDS-PAGE
31350
-
2 * 31350, SDS-PAGE
32200
2 * 32200, calculated from amino acid sequence
32638
-
x * 32638, calculated from sequence
33292
4 * 33292, calculated, 4 * 35086, MALDI-TOF
34500
-
2 * 34500, SDS-PAGE
34600
-
2 * 34600, SDS-PAGE
34689
-
x * 35000, SDS-PAGE, x * 34689, sequence calculation
35086
4 * 33292, calculated, 4 * 35086, MALDI-TOF
35300
-
4 * 35300, SDS-PAGE
35400
-
subunit of mitochondrial MDH, calculated from amino acid sequence
35560
-
x * 35000, recombinant enzyme, SDS-PAGE, x * 35560, plasma membrane-associated enzyme, sequence calculation
35600
-
2 * 35600, cytoplasmic form, SDS-PAGE
36100
-
4 * 36100, calculated from amino acid sequence
36400
-
subunit of cytosolic MDH, calculated from amino acid sequence
36517
x * 36517, calculated, x * 36000, SDS-PAGE, recombinant protein; x * 36517, cMDH, sequence calculation, x * 37340, C-terminally His-tagged cMDH, sequence calculation, x * 36000, His-tagged cMDH, SDS-PAGE
36600
-
4 * 36600, SDS-PAGE
36675
2 * 36675, MALDI-TOF mass spectrometry; 4 * 36675, MALDI-TOF mass spectrometry
37340
x * 36517, cMDH, sequence calculation, x * 37340, C-terminally His-tagged cMDH, sequence calculation, x * 36000, His-tagged cMDH, SDS-PAGE
39400
-
2 * 39400, SDS-PAGE
41000
-
subunit of mitochondrial MDH, SDS-PAGE
42000
-
subunit of cytosolic MDH, SDS-PAGE
43000
-
sedimentation equilibrium centrifugation
47000
-
2 * 47000, or tetramer, SDS-PAGE; or dimer, 4 * 47000, SDS-PAGE
52000
-
s-MDH
55000
-
x * 55000, SDS-PAGE
58000
-
2 * 58000, SDS-PAGE
60000 - 67000
-
sedimentation equilibrium centrifugation
60300
-
ultracentrifugation
61000
-
gel filtration
61700
-
gel filtration
64200
-
ultracentrifugation equlibrium
64400
calculated from amino acid sequence
68400
-
gel filtration
69500
-
both isoenzymes, sedimentation equilibrium
71000
-
gel filtration
71600
-
gel filtration
73350
dimeric enzyme, MALDI-TOF mass spectrometry
74000
-
-
74200
-
sedimentation equilibrium centrifugation
79120
-
sedimentation equilibrium method
83000
-
gel filtration
85040
-
sedimentation equilibrium method
86200
-
SDS-PAGE
92000
-
gel filtration
97000
-
gel filtration
105000
-
gel filtration
110000
-
cross-linking experiment
117000 - 148000
-
sedimentation equilibrium centrifugation
122000
-
gel filtration
123000
-
gel filtration
124000
-
gel filtration
125000
-
gel filtration
127000
-
gel filtration
128000
128500
-
ultracentrifugation; ultracentrifugation, sedimentation equilibrium studies
130000 - 140000
130000
133600
-
sedimentation equilibrium method
134000
134900
-
sedimentation equlibrium method
135000
-
gel filtration
137000
137100
-
N.C.A. 1518 Ra2, N.C.A. 1503, sedimentation equilibrium method
138000
138600
139000
-
gel filtration
140000
140900
-
sedimentation equilibrium method
142000
144000
-
cross-linking data
146000
-
cross-linking experiment
148000
150000
-
gel filtration; native enzyme, gel filtration
160000
170000
-
fusion protein of MDH with mitochondrial citrate synthase, gel filtration
172000
-
gel filtration
180000
244000
-
gel filtration