1.1.1.37: malate dehydrogenase

This is an abbreviated version, for detailed information about malate dehydrogenase, go to the full flat file.

Reaction

(S)-malate
+
NAD+
=
oxaloacetate
+
NADH
+
H+

Synonyms

(R)-2-hydroxyacid dehydrogenase, (S)-malate dehydrogenase, CaMDH, cMDH, cMDH -S, cMDH-L, cyMDH, cytosolic malate dehydrogenase, cytosolic MDH, cytosolic NAD-dependent malate dehydrogenase, halophilic malate dehydrogenase, HmMalDH, L-malate dehydrogenase, L-malate-NAD oxidoreductase, L-malate: NAD oxidoreductase, L-malate: NAD+ oxidoreductase, L-malate:NAD-oxidoreductase, L-MDH, m-MDH, malate (NAD) dehydrogenase, malate dehydrogenase, malate dehydrogenase (NAD), malate dehydrogenase 1, malate dehydrogenase 2, malate: NAD oxidoreductase, MalDH, malic acid dehydrogenase, malic dehydrogenase, mbNAD-MDH, MDH, MDH A, MDH B1, MDH B2, Mdh1, MDH2, Mdh2a, Mdh2b, mitochondrial malate dehydrogenase, mitochondrial MDH, mMDH, mNAD-MDH, More, NAD+-dependent malate dehydrogenase, NAD+-dependent MDH, NAD+-MDH enzymes, NAD-dependent malate dehydrogenase, NAD-dependent malic dehydrogenase, NAD-dependent MDH, NAD-L-malate dehydrogenase, NAD-linked malate dehydrogenase, NAD-malate dehydrogenase, NAD-malic dehydrogenase, NAD-MDH, NAD-specific malate dehydrogenase, Pcal_1699, peroxisomal NAD+-malate dehydrogenase 1, peroxisomal NAD+-malate dehydrogenase 2, PMDH, PMDH1, PMDH2, regulatory subunit of nucleic acid-conducting channel, s-MDH, SrMalDH, TaMDH, VEG69, Vegetative protein 69, YlMdh2p, [LDH-like] MDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.37 malate dehydrogenase

KM Value

KM Value on EC 1.1.1.37 - malate dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.056 - 15
(S)-malate
0.089
3-acetylnicotinamide-NAD+
-
-
0.0667
3-acetylpyridine adenine dinucleotide
-
-
0.04955 - 0.1114
3-acetylpyridine-adenine dinucleotide
0.022
Acetylpyridine adenine dinucleotide
pH 7.5
5.44
alpha-ketomalonate
pH 7.5
0.264
deamino-NAD+
-
-
2.2
Ketomalonate
-
-
0.014 - 20
L-malate
0.55 - 3.53
malate
0.022 - 3.32
NAD+
0.0014 - 1.4
NADH
0.178
NADP+
Coccochloris peniocystis
-
-
0.0426 - 0.25
NADPH
1.464
nicotinamide 1-N6-ethenoadenine dinucleotide
-
-
0.25
nicotinamide hypoxanthine dinucleotide
-
-
0.0024 - 29.4
oxaloacetate
2.7
p-hydroxyphenylpyruvate
-
0.19
pyridine 3-aldehyde adenine dinucleotide
-
-
2.2 - 2.9
pyruvate
0.37
reduced acetylpyridine adenine dinucleotide
pH 10.2
0.132
Thionicotinamide adenine dinucleotide
-
-
0.23
thionicotinamide-NAD+
-
-
additional information
additional information
-