1.1.1.365: D-galacturonate reductase
This is an abbreviated version!
For detailed information about D-galacturonate reductase, go to the full flat file.
Word Map on EC 1.1.1.365
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1.1.1.365
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l-ascorbic
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pectin
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ascorbate
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asa
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galurs
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dehydratase
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niger
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hypocrea
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ripening
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strawberry
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jecorina
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ripe
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l-galactono-1,4-lactone
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l-galactose
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trichoderma
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solanum
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reesei
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l-gulono-1,4-lactone
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pectin-rich
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gdp-d-mannose
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d-glucuronic
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dehydroascorbate
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synthesis
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nutrition
- 1.1.1.365
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l-ascorbic
- pectin
- ascorbate
- asa
- galurs
- dehydratase
- niger
-
hypocrea
-
ripening
- strawberry
- jecorina
-
ripe
- l-galactono-1,4-lactone
- l-galactose
-
trichoderma
-
solanum
- reesei
- l-gulono-1,4-lactone
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pectin-rich
- gdp-d-mannose
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d-glucuronic
- dehydroascorbate
- synthesis
- nutrition
Reaction
Synonyms
AKR2, AnGaaA, AnGar1, Cd-GAR, D-galacturonate reductase, D-galacturonic acid reductase, D-galacturonic acid reductases, FaGalUR, gaaA, GalA reductase, galacturonate reductase, GalUR, gar1, GAR2, NADPH-dependent D-galacturonate reductase, PcGOR
ECTree
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Substrates Products
Substrates Products on EC 1.1.1.365 - D-galacturonate reductase
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REACTION DIAGRAM
L-arabinose + NADPH + H+
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14.2% activity compared to D-glucuronate
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ir
L-galactose + NADPH + H+
?
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18.8% activity compared to D-glucuronate
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ir
?
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14.9% activity compared to D-glucuronate
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ir
D-galactose + NADPH + H+
?
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14.9% activity compared to D-glucuronate
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-
ir
D-galacturonate + NADH + H+
L-galactonate + NAD+
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17.7% activity compared to NADPH
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-
ir
L-galactonate + NADP+
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-
-
-
?
D-galacturonate + NADPH + H+
L-galactonate + NADP+
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-
-
-
?
D-galacturonate + NADPH + H+
L-galactonate + NADP+
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-
-
r
D-galacturonate + NADPH + H+
L-galactonate + NADP+
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-
-
?
D-galacturonate + NADPH + H+
L-galactonate + NADP+
HV538330
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-
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r
D-glucose + NADPH + H+
?
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14.6% activity compared to D-glucuronate
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-
ir
D-glucuronate + NADPH + H+
?
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82.4% activity compared to D-glucuronate
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-
?
D-glucuronate + NADPH + H+
?
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82.4% activity compared to D-glucuronate
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-
?
?
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14.2% activity compared to D-glucuronate
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ir
?
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the enzyme does not catalyze the reverse reaction with L-galactonate and NADP+ and does not utilize 4-nitrobenzaldehyde or menadione
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-
?
additional information
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the enzyme does not catalyze the reverse reaction with L-galactonate and NADP+ and does not utilize 4-nitrobenzaldehyde or menadione
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-
?
additional information
?
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HV538330
optimization of conversion of D-galacturonic acid to L-galactonic acid by recombinant enzyme in Saccharomyces cerevisiae, overview
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-
?
additional information
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optimization of conversion of D-galacturonic acid to L-galactonic acid by recombinant enzyme in Saccharomyces cerevisiae, overview
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-
?
additional information
?
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HV538330
optimization of conversion of D-galacturonic acid to L-galactonic acid by recombinant enzyme in Saccharomyces cerevisiae, overview
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-
?
additional information
?
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the enzyme catalyzes the reduction of the C-1 carbon of D-glucuronate and C-4 epimer D-galacturonate to their corresponding aldonic acids. It is active on both glucuronic acid and galacturonic acid, with similar substrate specificities using the preferred cosubstrate NADPH. Substrate acceptance extends to lactone congeners, and D-glucurono-3,6-lactone is converted to L-gulono-1,4-lactone
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-
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additional information
?
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no activity with NADH and D-glucose, D-fructose, D-xylose, D-galactose, L-arabinose, or D-mannose. No backward reaction with L-gulonic acid, glycerol, D-arabitol, L-arabitol, xylitol, galactitol, or ribitol
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-
?
additional information
?
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no activity with NADH and D-glucose, D-fructose, D-xylose, D-galactose, L-arabinose, or D-mannose. No backward reaction with L-gulonic acid, glycerol, D-arabitol, L-arabitol, xylitol, galactitol, or ribitol
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?