1.1.1.36: acetoacetyl-CoA reductase

This is an abbreviated version, for detailed information about acetoacetyl-CoA reductase, go to the full flat file.

Reaction

(R)-3-hydroxyacyl-CoA
+
NADP+
=
3-oxoacyl-CoA
+
NADPH
+
H+

Synonyms

(3R)-hydroxyacyl-CoA dehydrogenase, (R)-3-hydroxyacyl-CoA dehydrogenase, acetoacetyl CoA reductase, acetoacetyl coenzyme A reductase, acetoacetyl-CoA reductase, beta-ketoacyl reductase, beta-ketoacyl-CoA reductase, beta-ketoacyl-coenzyme A reductase, D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase, D-3-hydroxyacyl-CoA dehydrogenase, D-3-hydroxyacyl-CoA reductase, D-specific 3-hydroxyacyl-CoA dehydrogenase, hydroxyacyl coenzyme-A dehydrogenase, KCR, MFE-2, More, NADP-linked acetoacetyl CoA reductase, NADPH-dependent acetoacetyl-CoA reductase, NADPH-linked acetoacetyl-CoA reductase, NADPH:acetoacetyl-CoA reductase, PHA-specific acetoacetyl-CoA reductase, PhaB, PhbB, polyhydroxyalkanoate-specific acetoacetyl coenzyme A reductase, polyhydroxybutyrate enzyme, short chain beta-ketoacetyl(acetoacetyl)-CoA reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.36 acetoacetyl-CoA reductase

Natural Substrates Products

Natural Substrates Products on EC 1.1.1.36 - acetoacetyl-CoA reductase

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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(R)-3-hydroxybutyryl-CoA
trans-2-butenoyl-CoA + H2O
show the reaction diagram
-
dehydration, multifunctional type 2 enzyme
-
-
?
(R)-3-hydroxybutyryl-CoA + NAD+
acetoacetyl-CoA + NADH
show the reaction diagram
-
oxidation, multifunctional type 2 enzyme
-
-
?
(R)-3-hydroxybutyryl-CoA + NADPH + H+
3-oxobutyryl-CoA + NADP+
show the reaction diagram
-
-
-
-
r
acetoacetyl-CoA + NADH
D-3-hydroxybutyryl-CoA + NAD+
show the reaction diagram
-
PHA-synthesis
-
ir
acetoacetyl-CoA + NADH
L-3-hydroxybutyryl-CoA + NAD+
show the reaction diagram
acetoacetyl-CoA + NADPH
(R)-3-hydroxybutyryl-CoA + NADP+
show the reaction diagram
-
step in the biosynthesis of polyhydroxybutyrate, a biodegradable thermoplastic polymer
-
-
?
acetoacetyl-CoA + NADPH
?
show the reaction diagram
-
biosynthesis of poly(D-3-hydroxybutyrate)
-
-
-
acetoacetyl-CoA + NADPH
D-3-hydroxybutyryl-CoA + NADP+
show the reaction diagram
acetoacetyl-CoA + NADPH + H+
(R)-3-hydroxybutyryl-CoA + NADP+
show the reaction diagram
D-3-hydroxyacyl-CoA + NAD+
3-ketoacyl-CoA + NADH + H+
show the reaction diagram
additional information
?
-