1.1.1.343: phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating)
This is an abbreviated version!
For detailed information about phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating), go to the full flat file.
Word Map on EC 1.1.1.343
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1.1.1.343
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1.1.1.44
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glucose-6-phosphate
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4.1.3.8
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5.3.1.9
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3.1.3.11
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industry
- 1.1.1.343
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1.1.1.44
- glucose-6-phosphate
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4.1.3.8
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5.3.1.9
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3.1.3.11
- industry
Reaction
Synonyms
6-PGDH, 6-phospho-gluconate dehydrogenase, 6-phosphogluconate dehydrogenase, 6PGDH, EC 1.1.1.44, GND1, gndA, GNDl, gntZ, Gox1705, HVO_1830, NAD+-dependent 6-P gluconate dehydrogenase, NAD+-dependent 6-P-gluconate dehydrogenase, NAD+-dependent 6-phosphogluconate dehydrogenase, NAD+-dependent 6-phosphogluconate dehydrogenase (decarboxylating), NAD-dependent 6-phosphogluconate dehydrogenase (decarboxylating), NAD-dependent PGDH, NAD-specific 6-PGDH, NAD-specific 6-phosphogluconate dehydrogenase, phosphogluconate dehydrogenase
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.1.1.343 - phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating)
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REACTION DIAGRAM
D-ribulose 5-phosphate + CO2 + NADH + H+
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6-phospho-D-gluconate + NAD+
D-ribulose 5-phosphate + CO2 + NADH + H+
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6-phospho-D-gluconate + NAD+
D-ribulose 5-phosphate + CO2 + NADH + H+
the enzyme catalyzes an important reaction in the oxidative pentose phosphate pathway, producing a ribose precursor essential for nucleotide and nucleic acid synthesis
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6-phospho-D-gluconate + NAD+
D-ribulose 5-phosphate + CO2 + NADH + H+
the enzyme catalyzes an important reaction in the oxidative pentose phosphate pathway, producing a ribose precursor essential for nucleotide and nucleic acid synthesis
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6-phospho-D-gluconate + NAD+
D-ribulose 5-phosphate + CO2 + NADH + H+
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6-phospho-D-gluconate + NAD+
D-ribulose 5-phosphate + CO2 + NADH + H+
the enzyme is essential for the biosynthesis of pentose phosphates from glucose-6-phosphate during growth of Haloferax volcanii on glucose as growth substrate
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6-phospho-D-gluconate + NAD+
D-ribulose 5-phosphate + CO2 + NADH + H+
the enzyme is essential for the biosynthesis of pentose phosphates from glucose-6-phosphate during growth of Haloferax volcanii on glucose as growth substrate
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6-phospho-D-gluconate + NAD+
D-ribulose 5-phosphate + CO2 + NADH + H+
the wild type enzyme shows very low activity with NAD+, mutations at A30, R31, and T32 increase the catalytic activity with NAD+
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6-phospho-D-gluconate + NAD+
D-ribulose 5-phosphate + CO2 + NADH + H+
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