1.1.1.32: mevaldate reductase

This is an abbreviated version!
For detailed information about mevaldate reductase, go to the full flat file.

Reaction

Synonyms

mevalonic dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.32 mevaldate reductase

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Results	in table
1	CAS Registry Number
4	Cofactor
1	Inhibitors
3	KM Value [mM]
6	Natural Substrates/ Products (Substrates)
4	Organism
1	pH Optimum
1	pH Range
1	Purification (Commentary)
4	Reaction
1	Reaction Type
4	Reference
6	Source Tissue
2	Specific Activity [micromol/min/mg]
10	Substrates and Products (Substrate)
1	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 1.1.1.32 - mevaldate reductase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

3 entries

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+

3 entries

(S)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(S)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

3 entries

mevaldate + NADH + H+

(R)-mevalonate + NAD+

Sus scrofa

-

-

286554

-

-

r

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286553

-

286553

?

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286554

-

286554

ir

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286555

-

286555

ir

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+

Sus scrofa

-

-

286553

-

286553

?

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+

Sus scrofa

-

-

286554

-

286554

ir

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+

Sus scrofa

-

-

286555

-

286555

ir

(S)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(S)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286553

-

286553

?

(S)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(S)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286554

-

286554

ir

(S)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(S)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286555

-

286555

ir