1.1.1.32: mevaldate reductase

This is an abbreviated version, for detailed information about mevaldate reductase, go to the full flat file.

Reaction

(R)-mevalonate
+
NAD+
=
mevaldate
+
NADH
+
H+

Synonyms

mevalonic dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.32 mevaldate reductase

Substrates Products

Substrates Products on EC 1.1.1.32 - mevaldate reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH
(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+
show the reaction diagram
(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH
(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+
show the reaction diagram
(S)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH
(S)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+
show the reaction diagram