1.1.1.32: mevaldate reductase

This is an abbreviated version, for detailed information about mevaldate reductase, go to the full flat file.

Reaction

Synonyms

mevalonic dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.32 mevaldate reductase

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Results

in table

1

AA Sequence

1

CAS Registry Number

2

Cofactor

1

Inhibitors

3

KM Value [mM]

6

Natural Substrates/ Products (Substrates)

2

Organism

1

pH Optimum

1

pH Range

1

Purification (Commentary)

3

Reaction

1

Reaction Type

4

Reference by Title

4

Source Tissue

2

Specific Activity [micromol/min/mg]

9

Substrates and Products (Substrate)

1

Synonyms

1

Systematic Name

Substrates Products

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Substrates Products on EC 1.1.1.32 - mevaldate reductase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

3 entries

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+

3 entries

(S)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(S)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

3 entries

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286553

-

286553

-

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286554

-

286554

ir

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286555

-

286555

ir

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+

Sus scrofa

-

-

286553

-

286553

-

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+

Sus scrofa

-

-

286554

-

286554

ir

(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH

(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+

Sus scrofa

-

-

286555

-

286555

ir

(S)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(S)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286553

-

286553

-

(S)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(S)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286554

-

286554

ir

(S)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH

(S)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+

Sus scrofa

-

-

286555

-

286555

ir

Show Substrate/Product (9 entries)