1.1.1.31: 3-hydroxyisobutyrate dehydrogenase

This is an abbreviated version, for detailed information about 3-hydroxyisobutyrate dehydrogenase, go to the full flat file.

Reaction

3-hydroxy-2-methylpropanoate
+
NAD+
=
2-Methyl-3-oxopropanoate
 +
NADH
 +
H+

Synonyms

3-HIBADH, 3-hydroxyisobutyrate dehydrogenase, 3-hydroxyisobutyrate dehydrogenase-I, 3HIBDH-IV, 3HIBDHI, beta-hydroxyisobutyrate dehydrogenase, HIBADH, HIBDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.31 3-hydroxyisobutyrate dehydrogenase

Turnover Number

Turnover Number on EC 1.1.1.31 - 3-hydroxyisobutyrate dehydrogenase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.49
(R)-3-hydroxyisobutyrate
-
-
7.1 - 80.79
(S)-3-hydroxyisobutyrate
0.21
3-hydroxypropionate
-
; pH 8.5, 37°C
10.8 - 32.17
3-hydroxypropionic acid
47.16 - 47.55
L-serine
35.76 - 41.35
methyl (2S)-3-hydroxy-2-methylpropanoate
-
6.62 - 7.94
methyl DL-serine
-
6.717 - 15.1
NAD+