1.1.1.31: 3-hydroxyisobutyrate dehydrogenase

This is an abbreviated version, for detailed information about 3-hydroxyisobutyrate dehydrogenase, go to the full flat file.

Reaction

3-hydroxy-2-methylpropanoate
+
NAD+
=
2-Methyl-3-oxopropanoate
+
NADH
+
H+

Synonyms

3-HIBADH, 3-hydroxyisobutyrate dehydrogenase, 3-hydroxyisobutyrate dehydrogenase-I, 3HIBDH-IV, 3HIBDHI, beta-hydroxyisobutyrate dehydrogenase, HIBADH, HIBDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.31 3-hydroxyisobutyrate dehydrogenase

Temperature Stability

Temperature Stability on EC 1.1.1.31 - 3-hydroxyisobutyrate dehydrogenase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
45
-
enzyme activity is not decreased during preincubation at 45C within 30 min, but preincubation at 55C in 3 min can significantly denaturate and deactivate the enzyme; stable at 45C for 30 min, about 40% activity after 3 min at 55C