1.1.1.31: 3-hydroxyisobutyrate dehydrogenase

This is an abbreviated version, for detailed information about 3-hydroxyisobutyrate dehydrogenase, go to the full flat file.

Reaction

3-hydroxy-2-methylpropanoate
+
NAD+
=
2-Methyl-3-oxopropanoate
+
NADH
+
H+

Synonyms

3-HIBADH, 3-hydroxyisobutyrate dehydrogenase, 3-hydroxyisobutyrate dehydrogenase-I, 3HIBDH-IV, 3HIBDHI, beta-hydroxyisobutyrate dehydrogenase, HIBADH, HIBDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.31 3-hydroxyisobutyrate dehydrogenase

KM Value

KM Value on EC 1.1.1.31 - 3-hydroxyisobutyrate dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.12 - 0.652
(S)-3-hydroxyisobutyrate
83
2-methyl-D,L-serine
-
-
0.12
3-hydroxyisobutyric acid
-
-
16.8 - 18
3-hydroxypropionate
1.055 - 2.09
3-hydroxypropionic acid
0.1 - 0.12
D,L-3-hydroxyisobutyrate
1.25
D-3-hydroxyisobutyrate
-
-
0.056 - 0.37
L-3-hydroxyisobutyrate
31.84 - 117.5
L-serine
10.48 - 25.14
methyl (2S)-3-hydroxy-2-methylpropanoate
-
10.37 - 24.18
methyl DL-serine
-
0.022 - 2.4
NAD+
0.24 - 0.96
NADP+