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1.1.1.309: phosphonoacetaldehyde reductase (NADH)

This is an abbreviated version!
For detailed information about phosphonoacetaldehyde reductase (NADH), go to the full flat file.

Reaction

2-hydroxyethylphosphonate
+
NAD+
=
phosphonoacetaldehyde
+
NADH
+
H+

Synonyms

PhpC

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.309 phosphonoacetaldehyde reductase (NADH)

Systematic Name

Systematic Name on EC 1.1.1.309 - phosphonoacetaldehyde reductase (NADH)

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SYSTEMATIC NAME
IUBMB Comments
2-hydroxyethylphosphonate:NAD+ oxidoreductase
The enzyme from Streptomyces viridochromogenes catalyses a step in the biosynthesis of phosphinothricin tripeptide, the reduction of phosphonoacetaldehyde to 2-hydroxyethylphosphonate. The preferred cofactor is NADH, lower activity with NADPH [1].