1.1.1.30: 3-hydroxybutyrate dehydrogenase

This is an abbreviated version, for detailed information about 3-hydroxybutyrate dehydrogenase, go to the full flat file.

Reaction

(R)-3-hydroxybutanoate
+
NAD+
=
acetoacetate
+
NADH
+
H+

Synonyms

3-D-hydroxybutyrate dehydrogenase, 3-HBDH, 3-hydroxybutyrate dehydrogenase, 3-hydroxybutyrate dehydrogenase 2, 3-hydroxybutyrate dehydrogenase-2, 3HBDH, acetoacetyl-CoA reductase, BDH, BDH1, BDH2, BDH3, BdhA, beta-hydroxybutyrate dehydrogenase, beta-hydroxybutyric acid dehydrogenase, beta-hydroxybutyric dehydrogenase, D(-)-3-hydroxybutyrate dehydrogenase, D-(-)-3-hydroxybutyrate dehydrogenase, D-3-hydroxybutyrate dehydrogenase, D-beta-hydroxybutyrate dehydrogenase, DHRS6, HBD, HBDH, hydroxybutyrate oxidoreductase, More, NAD-beta-hydroxybutyrate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.30 3-hydroxybutyrate dehydrogenase

Molecular Weight

Molecular Weight on EC 1.1.1.30 - 3-hydroxybutyrate dehydrogenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
23000
-
alpha4, 4 * 23000, SDS-PAGE
31500
-
alpha4, 4 * 31500, SDS-PAGE
32000
-
alpha4, 4 * 32000, SDS-PAGE
33117
-
alpha4, 4 * 33117, mature protein, calculated from deduced amino acid sequence
38000
-
alpha4, 4 * 38000, preprotein, calculated from deduced amino acid sequence
39000
-
alpha4, 4 * 39000, SDS-PAGE
67000
-
x * 67000, SDS-PAGE
68000
-
nondenaturing PAGE
89000
-
gel filtration
106000
-
submitochondrial vesicles, radiation inactivation
110000
112000
-
gel filtration
119000
-
reconstituted enzyme, radiation inactivation, irradiation leads to loss of activity and fragmentation
120000
132000
-
gel filtration
140000
-
gel filtration