1.1.1.3: homoserine dehydrogenase

This is an abbreviated version, for detailed information about homoserine dehydrogenase, go to the full flat file.

Reaction

L-homoserine
+
NAD(P)+
=
L-aspartate 4-semialdehyde
+
NAD(P)H
+
H+

Synonyms

AK-HDH, AK-HSD-1, AK-HSDH, aspartate kinase-homoserine dehydrogenase, aspartokinase-homoserine dehydrogenase I, HDH, hom-1, homoserine dehydrogenase 1, homoserine dehydrogenase 2, HSD, HSDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.3 homoserine dehydrogenase

KCat KM Value

KCat KM Value on EC 1.1.1.3 - homoserine dehydrogenase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5.29 - 28.54
L-aspartate 4-semialdehyde
573
0.039 - 0.757
L-homoserine
345
0.281 - 0.53
NAD+
7
61.29 - 118.9
NADH
8
0.18 - 2.07
NADP+
10
101.4 - 331.2
NADPH
5