1.1.1.28: D-lactate dehydrogenase

This is an abbreviated version, for detailed information about D-lactate dehydrogenase, go to the full flat file.

Reaction

(R)-lactate
+
NAD+
=
pyruvate
+
NADH
+
H+

Synonyms

D-(-)-lactate dehydrogenase, D-(-)-lactate dehydrogenase (NAD), D-lactate dehydrogenase, D-lactic acid dehydrogenase, D-lactic dehydrogenase, D-LDH, D-LDH1, D-LDH2, D-LDH3, D-specific lactic dehydrogenase, dehydrogenase, D-lactate, DLDH, Fermentative lactate dehydrogenase, lactic acid dehydrogenase, LDH, Respiratory D-lactate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.28 D-lactate dehydrogenase

pH Optimum

pH Optimum on EC 1.1.1.28 - D-lactate dehydrogenase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3.6
-
pH 3.6 or pH 8.0, changes with pyruvate concentration
5
-
substrate pyruvate
5.8 - 6.5
-
-
6.4 - 7.5
-
-
6.4
-
reduction of pyruvate
7 - 7.5
8.2 - 9.7
8.2
-
substrate D-lactate
9
-
oxidation of (R)-lactate
10
-
isozyme D-LDH3
11
-
lactate oxidation reaction