1.1.1.28: D-lactate dehydrogenase

This is an abbreviated version, for detailed information about D-lactate dehydrogenase, go to the full flat file.

Reaction

(R)-lactate
+
NAD+
=
pyruvate
+
NADH
+
H+

Synonyms

D-(-)-lactate dehydrogenase, D-(-)-lactate dehydrogenase (NAD), D-lactate dehydrogenase, D-lactic acid dehydrogenase, D-lactic dehydrogenase, D-LDH, D-LDH1, D-LDH2, D-LDH3, D-specific lactic dehydrogenase, dehydrogenase, D-lactate, DLDH, Fermentative lactate dehydrogenase, lactic acid dehydrogenase, LDH, Respiratory D-lactate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.28 D-lactate dehydrogenase

Inhibitors

Inhibitors on EC 1.1.1.28 - D-lactate dehydrogenase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ba2+
-
slight inhibition at 1 mM
Fe2+
-
inhibits 25% at 1 mM
iodoacetamide
iodoacetate
Mn2+
-
slight inhibition at 1 mM
oxalate
oxamate
p-chloromercuribenzoate
-
-
p-Chloromercuriphenyl sulfonic acid
-
-
p-hydroxymercuribenzoate
phenylhydrazine
-
up to 45% inhibition
pyruvate
SDS
-
over 95% inhibition at 1 mM
Sodium arsenite
-
-
ZnSO4
-
1 mM, 80% inhibition, EDTA restores
additional information
-