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1.1.1.279: (R)-3-hydroxyacid-ester dehydrogenase

This is an abbreviated version!
For detailed information about (R)-3-hydroxyacid-ester dehydrogenase, go to the full flat file.

Reaction

ethyl (R)-3-hydroxyhexanoate
+
NADP+
=
ethyl 3-oxohexanoate
+
NADPH
+
H+

Synonyms

EC 1.2.1.55, reductase, 3-oxo ester (R)-

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.279 (R)-3-hydroxyacid-ester dehydrogenase

Systematic Name

Systematic Name on EC 1.1.1.279 - (R)-3-hydroxyacid-ester dehydrogenase

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SYSTEMATIC NAME
IUBMB Comments
ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase
Also acts on ethyl (R)-3-oxobutanoate and some other (R)-3-hydroxy acid esters. The (R)- symbol is allotted on the assumption that no substituents change the order of priority from O-3 > C-2 > C-4. A subunit of yeast fatty acid synthase EC 2.3.1.86, fatty-acyl-CoA synthase system. cf. EC 1.1.1.280, (S)-3-hydroxyacid ester dehydrogenase.